Table 1 Baseline characteristics of all patients (N = 137)
Variable | No. (%) or median (IQR) |
|---|---|
Age, yr | 64 (57, 72) |
Sex | |
 Male | 83 (60.6%) |
 Female | 54 (39.4%) |
BMI | 23.4 (22.0, 25.3) |
ECOG Performance status | |
 0 | 64 (46.7%) |
  ≥ 1 | 73 (53.3%) |
Chronic hepatitis B | 21 (15.3%) |
Chronic hepatitis C | 4 (2.9%) |
Hepatolithiasis | 17 (12.4%) |
Liver cirrhosis | 15 (10.9%) |
 Child-Pugh class A | 12 (8.8%) |
 Child-Pugh class B | 3 (2.2%) |
Diabetes mellitus | 25 (18.2%) |
Charlson Commorbidity Index | |
 0 | 87 (63.5%) |
  ≥ 1 | 50 (36.5%) |
Biliary drainage | 15 (10.9%) |
Tumor size, cm | 7.0 (5.0, 9.9) |
Major vascular invasion | 89 (65.0%) |
Hilar invasion | 16 (11.7%) |
Liver metastasis | 55 (40.1%) |
Extrahepatic organ metastasis | 75 (54.7%) |
 Peritoneum | 35 (25.5%) |
 Lung | 33 (24.1%) |
 Bone | 25 (18.2%) |
Distant lymph node metastasis | 90 (65.7%) |
Number of metastatic sites | |
 0 | 36 (26.3%) |
 1 | 59 (43.1%) |
  ≥ 2 | 42 (30.7%) |
Baseline laboratory findings | |
 White blood cell count, cells/μL | 8060 (6700, 9440) |
 Neutrophil count, cells/μL | 5606 (4126, 6751) |
 Lymphocyte count, cells/μL | 1612 (1346, 2029) |
 Monocyte count, cells/μL | 633 (509, 801) |
 Hemoglobin, g/dL | 12.6 ± 1.7 |
 Platelet count, 103 cells/μL | 237 (185, 281) |
 Albumin, g/dL | 4.0 (3.6, 4.2) |
 Globulin, g/dL | 3.2 (3.0, 3.6) |
 Total bilirubin, mg/dL | 0.7 (0.5, 0.9) |
 ALP, IU/L | 139 (98, 245) |
 AST, IU/L | 34 (24, 51) |
 ALT, IU/L | 26 (17, 44) |
 CA 19–9, U/mL | 266 (27, 4280) |
 Platelet-to-lymphocyte ratio | 133 (110, 186) |
 Neutrophil-to-lymphocyte ratio | 3.4 (2.3, 4.4) |
 Lymphocyte-to-monocyte ratio | 2.5 (2.1, 3.2) |
 Albumin-to-globulin ratio | 1.2 ± 0.3 |