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Table 3 Prognostic factors for disease-specific survival after diagnosis of metastasis

From: Prognostic factors of metastatic myxoid liposarcoma

(Cox-proportional hazards regression analysis)
   Univariate    Multivariable  
Variable HR 95%CI p-value HR 95%CI p-value
Male 2.18 0.80–5.92 0.13
Age (years)a 1.02 0.99–1.06 0.24
Time to metastasis (months)a 0.98 0.96–1.00 0.019* 0.99 0.97–1.00 0.17
Number of metastasesa 1.18 0.97–1.42 0.10
Size of largest metastasis (cm)a 1.08 0.96–1.20 0.18
Location of metastasis
 lung (n = 9) 2.28 0.87–5.39 0.09
 bone (n = 15) 1.01 0.41–2.32 0.97
 abdomen or retroperitoneum (n = 11) 1.65 0.59–4.02 0.32
 liver (n = 9) 4.14 1.60–10.2 0.005** 2.71 1.00–7.09 0.049*
NEDb following local treatment (n = 26) 4.45 1.86–11.5 0.0007** 0.36 0.13–0.95 0.040*
Chemotherapy for NEDb patients (n = 9) 1.95 0.52–7.30 0.32
  1. acalculated by unit hazard ratio, Interval from primary diagnosis to the first metastasis. It was defined as 0 month in M1 patients
  2. bNED: Status after completion of radical or semi-radical treatment for all of the remaining tumor
  3. * p <  0.05, **p < 0.01
  4. Abbreviations: HR hazard ratio; CI confidence interval
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