Table 3 Prognostic factors for disease-specific survival after diagnosis of metastasis

Variable

HR

95%CI

p-value

HR

95%CI

p-value

Male

2.18

0.80–5.92

0.13

–

–

–

Age (years)^a

1.02

0.99–1.06

0.24

–

–

–

Time to metastasis^‡ (months)^a

0.98

0.96–1.00

0.019*

0.99

0.97–1.00

0.17

Number of metastases^a

1.18

0.97–1.42

0.10

–

–

–

Size of largest metastasis (cm)^a

1.08

0.96–1.20

0.18

–

–

–

 lung (n = 9)

2.28

0.87–5.39

0.09

–

–

–

 bone (n = 15)

1.01

0.41–2.32

0.97

–

–

–

 abdomen or retroperitoneum (n = 11)

1.65

0.59–4.02

0.32

–

–

–

 liver (n = 9)

4.14

1.60–10.2

0.005**

2.71

1.00–7.09

0.049*

4.45

1.86–11.5

0.0007**

0.36

0.13–0.95

0.040*

Chemotherapy for NED^b patients (n = 9)

1.95

0.52–7.30

0.32

–

–

–