Table 2 Adverse events according to the Common Terminology Criteria for Adverse Events, version 5.0
Adverse event, n (%) | Grade 1–2 | Grade 3–4 |
|---|---|---|
White blood cell decreased | 1 (4) | 24 (96) |
Anemia | 8 (32) | 17 (68) |
Febrile neutropenia | – | 17 (68) |
Platelet count decreased | 13 (52) | 12 (48) |
Alanine aminotransferase increased | 3 (12) | 5 (20) |
Aspartate aminotransferase increased | 5 (20) | 3 (12) |
Alopecia | 25 (100) | 0 (0) |
Nausea | 17 (68) | 0 (0) |
Fatigue | 11 (44) | 0 (0) |
Constipation | 8 (32) | 0 (0) |
Diarrhea | 8 (32) | 0 (0) |
Dyspepsia | 7 (28) | 0 (0) |
Hiccups | 6 (24) | 0 (0) |
Vomiting | 5 (20) | 0 (0) |
Mucositis oral | 4 (16) | 0 (0) |
Insomnia | 3 (12) | 0 (0) |
Hematuria | 2 (8) | 0 (0) |
Dysgeusia | 2 (8) | 0 (0) |
Arthralgia | 2 (8) | 0 (0) |
Urticaria | 1 (4) | 0 (0) |
Delirium | 1 (4) | 0 (0) |
Creatinine increased | 0 (0) | 0 (0) |
Heart failure | 0 (0) | 0 (0) |