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Fig. 4 | BMC Cancer

Fig. 4

From: Chemotherapy-induced release of circulating-tumor cells into the bloodstream in collective migration units with cancer-associated fibroblasts in metastatic cancer patients

Fig. 4

CTC mobilization with different chemotherapeutic regimens. a Box and whisker charts show the fold change in CTC counts after 1 and 2 cycles of treatment with: A combination of Fluorouracil, Oxaliplatin and Irinotecan, or alkylating agent-, plant alkaloids-, antimetabolite- and inhibitor-based chemotherapy. Lines connect individual patients (median ± range, N = 72 from 30 Met-pa). The changes in the median CTC level over the course of each treatment was tested for significance with a paired Wilcoxon test. b Box and whisker plots represent the fold change in CTC counts post-chemotherapy in patients showing continuous progression of cancer. Lines connect individual patients (median ± range, N = 9 from 3 Met-pa). The change in median CTC level post-treatment was not significant using a paired Wilcoxon test (0.500 < P > 0.999)

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BMC Cancer

ISSN: 1471-2407

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