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Fig. 2 | BMC Cancer

Fig. 2

From: Tumor quiescence: elevating SOX2 in diverse tumor cell types downregulates a broad spectrum of the cell cycle machinery and inhibits tumor growth

Fig. 2

SOX2 elevation inhibits the proliferation of Medulloblastoma and Neuroblastoma cells in vitro. a Western blot analysis of whole cell extracts from i-SOX2-ONS76 and i-SOX2-BE(2)C cells cultured for 48 h with the indicated doses of Dox. b Proliferation of i-SOX2-ONS76 and i-SOX2-BE(2)C cells was determined by MTT assay following 4 days culture in the presence or absence of Dox at the indicated doses. Error bars represent standard deviation. c Relative EdU incorporation of i-SOX2-ONS76 and i-SOX2-BE(2)C cells following 4 days of culture in the presence or absence of Dox at the indicated doses

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BMC Cancer

ISSN: 1471-2407

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