|
Factors
|
N
|
LNM(−),n(%)
|
LNM(+),n(%)
|
P-value
|
|---|
|
N
|
288
|
271
|
17
| |
|
Gender
| | | |
0.431
|
|
Male
|
162
|
154 (53.47)
|
8 (47.06)
| |
|
Female
|
126
|
117 (46.53)
|
9 (52.94)
| |
|
Age,χ ± SD (years old)
|
59.5 + 11.6
|
59.7 + 11.7
|
56.8 + 11.2
|
0.316
|
|
Smoking
| | | |
0.084
|
|
Positive
|
68
|
67 (23.26)
|
1 (5.88)
| |
|
Negative
|
220
|
204 (76.74)
|
16 (94.12)
| |
|
Alcohol
| | | |
0.520
|
|
Positive
|
43
|
41 (15.13)
|
2 (11.76)
| |
|
Negative
|
245
|
230 (84.87)
|
15 (88.24)
| |
|
Family history
| | | |
0.557
|
|
Positive
|
10
|
10 (3.69)
|
(0.00)
| |
|
Negative
|
278
|
261 (96.31)
|
17 (100.00)
| |
|
Tumor size, χ ± SD (mm)
|
30.0 ± 15.6
|
29.2 ± 15.4
|
38.3 ± 17.3
|
0.026*
|
|
Tumor location
| | | |
0.115
|
|
Rectum
|
186
|
171 (63.10)
|
15 (88.24)
| |
|
Sigmoid colon
|
68
|
68 (25.09)
|
0
| |
|
Ascending colon
|
19
|
17 (6.27)
|
2 (11.76)
| |
|
Descending colon
|
10
|
10 (3.69)
|
0
| |
|
Transverse colon
|
5
|
5 (1.85)
|
0
| |
|
Endoscopic morphology
| | | |
0.703
|
|
I (the uplift type)
|
248
|
232 (85.61)
|
16 (94.12)
| |
|
II (the flat type)
|
7
|
7 (2.58)
|
0 (0.00)
| |
|
III (the concave type)
|
25
|
24 (8.86)
|
1 (5.88)
| |
|
Uncertain
|
8
|
8 (2.95)
|
0 (0.00)
| |
|
Pathology
| | | |
< 0.001**
|
|
Highly differentiated
|
78
|
78 (28.78)
|
0 (0.00)
| |
|
Moderately differentiated
|
202
|
189 (69.74)
|
13 (76.47)
| |
|
Poorly differentiated
|
8
|
4 (1.48)
|
4 (23.53)
| |
|
Depth of invasion
| | | |
0.255
|
|
Mucosal layer
|
76
|
74 (27.31)
|
2 (11.76)
| |
|
Submucosal layer
|
212
|
197 (72.69)
|
15 (88.24)
| |
|
Lympho-vascular invasion
| | | |
< 0.001**
|
|
Positive
|
6
|
2 (0.74)
|
4 (23.53)
| |
|
Negative
|
282
|
269 (99.26)
|
13 (76.47)
| |
|
Tumor budding
| | | |
0.833
|
|
Positive
|
3
|
3 (1.11)
|
0 (0.00)
| |
|
Negative
|
285
|
268 (98.89)
|
17 (100.00)
| |
- Note: * P < 0.05, ** P < 0.01. LNM(−):No lymph node metastasis, LNM(+):Lymph node metastasis
