Table 1 Patient characteristics in patients with LARC after NCRT
Characteristics | Young group (n = 75) | Old group (n = 826) | p value |
|---|---|---|---|
Sex (%) | 0.527 | ||
Male | 52 (69.3) | 537 (65.0) | |
Female | 23 (30.7) | 289 (35.0) | |
Age (years) | 34.3 ± 4.1 | 58.1 ± 9.4 | < 0.001 |
ASA score (%) | < 0.001 | ||
1 | 75 (100) | 603 (73.0) | |
2 | 0 | 209 (25.3) | |
3 | 0 | 14 (1.6) | |
Distance from the anal verge (cm) | 6.4 ± 2.5 | 6.3 ± 2.3 | 0.684 |
Time interval between CRT and surgery (weeks) | 9.1 ± 1.4 | 9.4 ± 2.9 | 0.468 |
Clinical T stage (%) | 0.173 | ||
T1 | 1 (1.3) | 2 (0.2) | |
T2 | 0 | 18 (2.2) | |
T3 | 25 (33.3) | 317 (38.4) | |
T4 | 49 (65.3) | 489 (59.7) | |
Clinical N stage (%) | 1.000 | ||
N0 | 7 (9.3) | 79 (9.5) | |
N+ | 68 (90.7) | 747 (90.5) | |
Pre-NCRT CEA level (%) | 0.562 | ||
< 5.0 ng/ml | 25(33.3) | 283 (34.3) | |
≥ 5.0 ng/ml | 24(32.0) | 219 (26.5) | |
Unknown | 26(34.7) | 324 (39.2) | |
Pre-NCRT CA19–9 level (%) | 0.641 | ||
< 39.0 U/ml | 40 (53.3) | 430 (52.1) | |
≥ 39.0 U/ml | 9 (12.0) | 76 (9.2) | |
Unknown | 26(34.7) | 320 (38.7) | |
Post-NCRT CEA level (%) | 0.115 | ||
< 5.0 ng/ml | 67 (89.3) | 672 (81.4) | |
≥ 5.0 ng/ml | 8 (10.7) | 154 (18.6) | |
Post-NCRT CA19–9 level (%) | 0.320 | ||
< 39.0 U/ml | 68 (90.7) | 775 (93.8) | |
≥ 39.0 U/ml | 7 (9.3) | 51 (6.2) |