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Table 2 Multivariate Cox regression analysis for independent prognosis factors

From: Survival analysis of patients with stage T2a and T2b perihilar cholangiocarcinoma treated with radical resection

Variable name

HR

95.0% CI

P value

Lower

Upper

TBIL(≥157.4umol/L)

1.334

0.868

2.051

0.189

AST(≥85.0 IU/L)

1.508

1.014

2.243

0.042*

CA19–9(≥1000.0 U/mL)

1.975

1.215

3.210

0.006*

Vascular resection

3.166

1.312

7.638

0.010*

Perineural invasion

1.835

0.881

3.823

0.105

Resection margin status

1.486

0.854

2.585

0.161

Postoperative complication

1.732

0.959

3.126

0.068

Pathological differentiation

   

0.003*

 Well

Ref.

 Moderate

1.721

0.760

3.897

0.193

 Poor

3.591

1.486

8.675

0.005*

N staging

   

0.605

 N0

Ref.

 N1

1.256

0.791

1.995

0.335

 N2

1.166

0.568

2.396

0.676

  1. NOTE. TBIL, total bilirubin; AST, aspartate amino transferase; CA19–9, carbohydrate antigen 19–9
  2. The cutoff value of TBIL, AST were their median respectively; the cutoff value of CA19–9 was the upper limit of threshold level
  3. Significant variables with P < 0.05 in the univariate analysis were included in the multivariate Cox PH models regression analyses
  4. * P value< 0.05