|
Characteristic
|
n (%)
|
Age at diagnosis, years (percent within age group)
|
P
|
|---|
|
< 50
|
50–59
|
60–69
|
70–79
|
> 80
|
|---|
|
Sex
|
|
Male
|
11,886 (96.95)
|
574 (76.84)
|
2052 (78.50)
|
3830 (77.94)
|
3916 (74.95)
|
1514 (71.28)
| |
|
Female
|
3738 (3.05)
|
173 (23.16)
|
562 (21.50)
|
1084 (22.06)
|
1309 (25.05)
|
610 (28.72)
|
< 0.001
|
|
Year of diagnosis
|
|
1988 to 2003
|
3717 (23.79)
|
221 (29.59)
|
649 (24.83)
|
1081 (22.00)
|
1323 (25.32)
|
443 (20.86)
| |
|
2004 to 2015
|
11,907 (76.21)
|
526 (70.41)
|
1965 (75.17)
|
3833 (78.00)
|
3902 (74.68)
|
1681 (79.14)
|
< 0.001
|
|
Race
|
|
Caucasians
|
13,929 (89.15)
|
634 (84.87)
|
2260 (86.46)
|
4387 (89.28)
|
4718 (90.30)
|
1930 (90.87)
| |
|
Afro-Americans
|
918 (5.88)
|
73 (9.77)
|
220 (8.42)
|
308 (6.27)
|
238 (4.56)
|
79 (3.72)
| |
|
Other
|
751 (4.81)
|
37 (4.95)
|
128 (4.90)
|
211 (4.29)
|
264 (5.05)
|
111 (5.23)
| |
|
Unknown
|
26 (0.17)
|
3 (0.40)
|
6 (0.23)
|
8 (0.16)
|
5 (0.10)
|
4 (0.19)
|
< 0.001
|
|
Grade
|
|
I
|
60 (0.38)
|
9 (1.20)
|
8 (0.31)
|
13 (0.26)
|
19 (0.36)
|
11 (0.52)
| |
|
II
|
469 (3.00)
|
28 (3.75)
|
96 (3.67)
|
139 (2.83)
|
152 (2.91)
|
54 (2.54)
| |
|
III
|
5388 (34.49)
|
272 (36.41)
|
907 (34.70)
|
1660 (33.78)
|
1836 (35.14)
|
713 (33.57)
| |
|
IV
|
9181 (58.76)
|
415 (55.56)
|
1512 (57.84)
|
2948 (59.99)
|
3035 (58.09)
|
1271 (59.84)
| |
|
Unknown
|
526 (3.37)
|
23 (3.08)
|
91 (3.48)
|
154 (3.13)
|
183 (3.50)
|
75 (3.53)
|
0.01
|
|
T stage
|
|
T2
|
6353 (40.66)
|
331 (44.31)
|
1138 (43.53)
|
2141 (43.57)
|
2053 (39.29)
|
690 (32.49)
| |
|
T3
|
6479 (41.47)
|
281 (37.62)
|
1034 (39.56)
|
1897 (38.60)
|
2230 (42.68)
|
1037 (48.82)
| |
|
T4
|
2792 (17.87)
|
135 (18.07)
|
442 (16.91)
|
876 (17.83)
|
942 (18.03)
|
397 (18.69)
|
< 0.001
|
- Characteristics differ by age group; Grade represents the degree of differentiation of bladder tumor (Grade I: Well differentiated, Grade II: Moderately differentiated, Grade III: Poorly differentiated, Grade IV: Undifferentiated); Year of diagnosis represents the time of diagnosis of MIBC; T stage represents the degree of invasion of bladder tumor
