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Table 3 Univariate and multivariate analyses of the overall survival of the 161 TNBC patients

From: ANGPTL4 overexpression inhibits tumor cell adhesion and migration and predicts favorable prognosis of triple-negative breast cancer

Variable

Overall survival

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

Age ≤ 40 years old

1.133 (0.549–2.340)

0.736

  

Family history of cancer

1.572 (0.705–3.505)

0.269

  

Menstruating

1.131 (0.641–1.996)

0.670

  

History of other neoplasms

1.232 (0.299–5.086)

0.773

  

Stage III disease

4.420 (2.496–7.827)

0.000

2.493 (1.276–4.873)

0.008

T3/ T4

2.567 (1.391–4.735)

0.003

0.995 (0.436–2.271)

0.497

Lymph node metastasis

4.440 (2.262–8.713)

0.000

2.543 (1.151–5.620)

0.021

Poor tumor differentiation

1.547 (0.788–3.040)

0.205

  

Vascular invasion

3.567 (2.002–6.355)

0.000

1.725 (0.841–3.535)

0.102

Distant metastasis

1.775 (0.899–3.503)

0.098

  

Low ANGPTL4 expression

2.180 (1.232–3.860)

0.006

1.776 (0.998–3.161)

0.051

  1. Stage III disease, lymph node metastasis and low ANGPTL4 expression are independent risk factors for shorter OS