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Table 3 Univariate and multivariate analyses of the overall survival of the 161 TNBC patients

From: ANGPTL4 overexpression inhibits tumor cell adhesion and migration and predicts favorable prognosis of triple-negative breast cancer

Variable Overall survival
Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P value
Age ≤ 40 years old 1.133 (0.549–2.340) 0.736   
Family history of cancer 1.572 (0.705–3.505) 0.269   
Menstruating 1.131 (0.641–1.996) 0.670   
History of other neoplasms 1.232 (0.299–5.086) 0.773   
Stage III disease 4.420 (2.496–7.827) 0.000 2.493 (1.276–4.873) 0.008
T3/ T4 2.567 (1.391–4.735) 0.003 0.995 (0.436–2.271) 0.497
Lymph node metastasis 4.440 (2.262–8.713) 0.000 2.543 (1.151–5.620) 0.021
Poor tumor differentiation 1.547 (0.788–3.040) 0.205   
Vascular invasion 3.567 (2.002–6.355) 0.000 1.725 (0.841–3.535) 0.102
Distant metastasis 1.775 (0.899–3.503) 0.098   
Low ANGPTL4 expression 2.180 (1.232–3.860) 0.006 1.776 (0.998–3.161) 0.051
  1. Stage III disease, lymph node metastasis and low ANGPTL4 expression are independent risk factors for shorter OS