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Table 2 Univariate and multivariate analyses of the disease-free survival of the 161 TNBC patients

From: ANGPTL4 overexpression inhibits tumor cell adhesion and migration and predicts favorable prognosis of triple-negative breast cancer

Variable

 

Disease-free survival

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

Age ≤ 40 years old

1.090 (0.527–2.254)

0.817

  

Family history of cancer

0.649 (0.290–1.448)

0.291

  

Menstruating

1.321 (0.738–2.366)

0.348

  

History of other neoplasms

1.321 (0.320–5.449)

0.700

  

Stage III disease

3.918 (2.203–6.967)

0.000

2.163 (1.121–4.172)

0.021

T3/ T4

2.083 (1.098–3.951)

0.025

0.870 (0.357–2.119)

0.771

Lymph node metastasis

4.502 (2.287–8.863)

0.000

2.890 (1.330–6.277)

0.007

Poor tumor differentiation

1.426 (0.683–2.979)

0.345

  

Vascular invasion

2.983 (1.639–5.429)

0.000

1.558 (0.731–3.320)

0.255

Low ANGPTL4 expression

2.283 (1.280–4.075)

0.004

2.005 (1.121–3.585)

0.019

  1. Stage III disease, lymph node metastasis and low ANGPTL4 expression are independent risk factors for shorter DFS