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Table 2 Univariate and multivariate analyses of the disease-free survival of the 161 TNBC patients

From: ANGPTL4 overexpression inhibits tumor cell adhesion and migration and predicts favorable prognosis of triple-negative breast cancer

Variable   Disease-free survival
Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P value
Age ≤ 40 years old 1.090 (0.527–2.254) 0.817   
Family history of cancer 0.649 (0.290–1.448) 0.291   
Menstruating 1.321 (0.738–2.366) 0.348   
History of other neoplasms 1.321 (0.320–5.449) 0.700   
Stage III disease 3.918 (2.203–6.967) 0.000 2.163 (1.121–4.172) 0.021
T3/ T4 2.083 (1.098–3.951) 0.025 0.870 (0.357–2.119) 0.771
Lymph node metastasis 4.502 (2.287–8.863) 0.000 2.890 (1.330–6.277) 0.007
Poor tumor differentiation 1.426 (0.683–2.979) 0.345   
Vascular invasion 2.983 (1.639–5.429) 0.000 1.558 (0.731–3.320) 0.255
Low ANGPTL4 expression 2.283 (1.280–4.075) 0.004 2.005 (1.121–3.585) 0.019
  1. Stage III disease, lymph node metastasis and low ANGPTL4 expression are independent risk factors for shorter DFS