Table 1 Associations between angiopoietin-like 4 (ANGPTL4) expression and clinicopathologic factors of 161 patients with TNBC
Characteristics | ANGPTL4 expression (cases) | P value | |
|---|---|---|---|
Weak | High | ||
Total | 66 | 95 | Â |
Age (years) | |||
  ≤ 40 | 9 (13.6%) | 20 (21.1%) | 0.228 |
  > 40 | 57 (86.4%) | 75 (78.9%) |  |
Family history of cancer | Â | Â | 0.600 |
 No | 52 (78.8%) | 78 (82.1%) |  |
 Yes | 14 (21.2%) | 17 (17.9%) |  |
Menopause | Â | Â | 0.435 |
 No | 32 (51.5%) | 52 (45.3%) |  |
 Yes | 34 (48.5%) | 43 (54.7%) |  |
History of other neoplasms | Â | Â | 0.601 |
 No | 63 (95.5%) | 92 (96.8%) |  |
 Yes | 3 (4.5%) | 3 (3.2%) |  |
Stage | Â | Â | 0.265 |
 0/ I/ II | 44 (66.7%) | 71 (74.7%) |  |
 III | 22 (33.3%) | 24 (25.3%) |  |
T status | Â | Â | 0.395 |
 Tis/ T1/ T2 | 55 (83.3%) | 74 (77.9%) |  |
 T3/ T4 | 11 (16.7%) | 21 (22.1%) |  |
Lymph node metastasis | Â | Â | 0.139 |
 N0 | 29 (43.9%) | 53 (55.8%) |  |
 N1–3 | 37 (56.1%) | 42 (44.2%) |  |
Histological differentiation | Â | Â | 0.087 |
 1/ 2 | 24 (50.0%) | 26 (38.6%) |  |
 3 | 21 (50.0%) | 44 (61.4%) |  |
Vascular invasion | |||
 No | 47 (71.2%) | 80 (84.2%) | 0.047 |
 Yes | 19 (28.8%) | 15 (15.8%) |  |
Disease recurrence | |||
 No | 39 (59.1%) | 75 (78.9%) | 0.006 |
 Yes | 27 (40.9%) | 20 (21.1%) |  |
Progression | Â | Â | 0.333 |
 Local recurrence | 16 (59.3%) | 9 (45.0%) |  |
 Distant metastasis | 11 (40.7%) | 11 (55.0%) |  |