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Fig. 3 | BMC Cancer

Fig. 3

From: ANGPTL4 overexpression inhibits tumor cell adhesion and migration and predicts favorable prognosis of triple-negative breast cancer

Fig. 3

ANGPTL4 overexpression decreases the mRNA levels of ECM-related genes. a Next-generation RNA sequencing revealed that genes related to adherens junctions, blood vessel morphogenesis, extracellular matrix and wound healing were most affected by ANGPTL4 overexpression. b Real-time quantitative PCR confirmed that ten genes were downregulated in the 231 ANGPTL4 OE group compared with the control group. These results suggest that ANGPTL4 overexpression might affect TNBC progression by inhibiting ECM-related genes (Graghpad Prism statistical software package, version 5.01, *p < 0.05)

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BMC Cancer

ISSN: 1471-2407

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