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Table 5 Comparison of cytology alone, HR-HPV testing alone, and co-testing

From: Outcomes of prior cervical cytology and HR-HPV testing in women subsequently diagnosed with CIN1, CIN2/3, and invasive cervical cancer: a 4-year routine clinical experience after implementation of systematic training and quality control programs

Screening modality

CIN1 (n = 1829)

CIN2/3 (n = 2308)

ICC (n = 680)

Sensitivity, %

95% CI

Sensitivity, %

95% CI

Sensitivity, %

95% CI

Cytology alone

92.9 (520/560)

90.7–95.0

97.2 (854/879)

96.1–98.3

89.1 (205/230)

85.1–93.2

HR-HPV testing alone

79.9 (570/713)

77.0–82.9

95.4 (864/906)

94.0–96.7

92.7 (204/220)

89.3–96.2

Co-testing

95.3 (530/556)

93.6–97.1

99.8 (523/524)

99.4–100

99.6 (229/230)

98.7–100

  1. HR-HPV high-risk human papillomavirus, CIN cervical intraepithelial neoplasia, ICC invasive cervical cancer, CI confidence interval