Skip to main content

Table 4 Results of cytology and HR-HPV co-testing

From: Outcomes of prior cervical cytology and HR-HPV testing in women subsequently diagnosed with CIN1, CIN2/3, and invasive cervical cancer: a 4-year routine clinical experience after implementation of systematic training and quality control programs

Cytological interpretation

HR-HPV testing

Total

HC2 testing

Genotyping

Negative (%)

Positive (%)

Negative (%)

Positive (%)

Negative (%)

Positive (%)

CIN1 (n = 556)

 NILM

3 (1.5)

14 (7.2)

23 (6.4)

27 (7.5)

26 (4.7)

41 (7.4)

 ASC-US

20 (10.3)

49 (25.3)

40 (11.0)

91 (25.1)

60 (10.8)

140 (25.2)

 ASC-H

2 (1.0)

4 (2.1)

3 (0.8)

3 (0.8)

5 (0.9)

7 (1.3)

 LSIL

18 (9.3)

79 (40.7)

38 (10.5)

130 (35.9)

56 (10.1)

209 (37.6)

 HSIL

3 (1.5)

2 (1.0)

1 (0.3)

6 (1.7)

4 (0.7)

8 (1.4)

Total

46 (23.7)

148 (76.3)

105 (29.0)

257 (71.0)

151 (27.2)

405 (72.8)

CIN2/3 (n = 524)

 NILM

0 (0)

12 (5.6)

1 (0.3)

25 (8.0)

1 (0.2)

37 (7.1)

 ASC-US

2 (0.9)

33 (15.5)

7 (2.3)

53 (17.0)

9 (1.7)

86 (16.4)

 ASC-H

2 (0.9)

35 (16.4)

2 (0.6)

22 (7.1)

4 (0.8)

57 (10.9)

 LSIL

4 (1.9)

52 (24.4)

6 (1.9)

74 (23.8)

10 (1.9)

126 (24.0)

 HSIL

5 (2.3)

68 (31.9)

9 (2.9)

112 (36.0)

14 (2.7)

180 (34.4)

Total

13 (6.1)

200 (93.9)

25 (8.0)

286 (92.0)

38 (7.3)

486 (92.7)

ICC (n = 230)

 NILM

0 (0)

3 (7.3)

1 (0.5)

6 (3.2)

1 (0.4)

9 (3.9)

 Unsatisfactory

0 (0)

0 (0)

0 (0)

5 (2.6)

0 (0)

5 (2.2)

 ASC-US

1 (2.4)

3 (7.3)

3 (1.6)

15 (7.9)

4 (1.7)

18 (7.8)

 ASC-H

0 (0)

10 (24.4)

1 (0.5)

29 (15.3)

1 (0.4)

39 (17.0)

 LSIL

0 (0)

0 (0)

0 (0)

1 (0.5)

0 (0)

1 (0.4)

 HSIL

0 (0)

18 (43.9)

1 (0.5)

100 (52.9)

1 (0.4)

118 (51.3)

 AGC

0 (0)

0 (0)

2 (1.1)

3 (1.6)

2 (0.9)

3 (1.3)

 Cancer cells

0 (0)

6 (14.6)

3 (1.6)

19 (10.1)

3 (1.3)

25 (10.9)

Total

1 (2.4)

40 (97.6)

11 (5.8)

178 (94.2)

12 (5.2)

218 (94.8)

  1. HR-HPV high-risk human papillomavirus, CIN cervical intraepithelial neoplasia, ICC invasive cervical cancer, NILM negative for intraepithelial lesion or malignancy, ASC-US atypical squamous cells of undetermined significance, ASC-H atypical squamous cells-cannot exclude HSIL, LSIL low-grade squamous intraepithelial lesion, HSIL high-grade squamous intraepithelial lesion, AGC atypical glandular cells, HC2 Hybrid Capture 2