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Table 3 Association between parental occupational exposure to pesticides and risk of childhood cancer in the Swiss National Cohort; leukaemia and lymphoma subtypes

From: Parental occupational exposure to pesticides and risk of childhood cancer in Switzerland: a census-based cohort study

  

Paternal exposure

Maternal exposure

Outcome

Likelihood of Exposure

Cases

Partially adjusted model1

Fully adjusted model2

Cases

Partially adjusted model1

Fully adjusted model2

  

n

HR [95%CI]

HR [95%CI]

n

HR [95%CI]

HR [95%CI]

LL

Minimal

332

1

1

397

1

1

High

19

0.77 [0.48–1.22]

0.73 [0.41–1.31]

8

0.76 [0.38–1.54]

0.69 [0.28–1.71]

AML

Minimal

75

1

1

84

1

1

High

3

0.53 [0.17–1.68]

0.97 [0.29–3.25]

1

0.42 [0.06–3.04]

0.86 [0.11–6.50]

NHL

Minimal

151

1

1

166

1

1

High

8

0.69 [0.34–1.41]

0.75 [0.32–1.75]

4

0.84 [0.31–2.27]

1.16 [0.41–3.23]

HL

Minimal

140

1

1

162

1

1

High

13

1.21 [0.68–2.13]

1.43 [0.74–2.77]

4

0.89 [0.33–2.41]

1.27 [0.45–3.56]

  1. LL: lymphoid leukaemia; AML: acute myeloid leukaemia; NHL: Non-Hodgkin lymphoma; HL: Hodgkin lymphoma; HR: Hazard Ratio estimated with a Cox regression; 95%CI: 95% confidence interval
  2. 1Model adjusted for sex, birth year and census year at entry
  3. 2Model adjusted for sex, birth year, census year at entry, maternal age at birth, paternal and maternal occupational exposure to benzene, education level of the reference person in the household, SEP-index, degree of urbanization, residential exposure to background ionizing radiation, residential exposure to ambient NO2 (All variables assessed at entry into the cohort)