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Table 2 Association between parental occupational exposure to pesticides and risk of childhood cancer in the Swiss National Cohort; major diagnostic groups only

From: Parental occupational exposure to pesticides and risk of childhood cancer in Switzerland: a census-based cohort study

  

Paternal exposure

Maternal exposure

Outcome

Likelihood of

Exposure

Cases

Partially adjusted model1

Fully adjusted model2

Cases

Partially adjusted model1

Fully adjusted model2

  

n

HR [95%CI]

HR [95%CI]

n

HR [95%CI]

HR [95%CI]

Any cancer

Minimal

1559

1

1

1808

1

1

High

112

0.95 [0.79–1.16]

1.14 [0.91–1.43]

49

1.00 [0.75–1.33]

1.13 [0.82–1.56]

Leukaemia

Minimal

438

1

1

515

1

1

High

24

0.73 [0.49–1.10]

0.79 [0.48–1.29]

9

0.66 [0.34–1.27]

0.66 [0.29–1.49]

Lymphoma

Minimal

297

1

1

333

1

1

High

21

0.92 [0.59–1.43]

1.06 [0.63–1.78]

9

0.96 [0.49–1.86]

1.18 [0.57–2.44]

CNST

Minimal

345

1

1

405

1

1

High

20

0.78 [0.50–1.22]

0.76 [0.44–1.33]

8

0.77 [0.38–1.55]

0.65 [0.26–1.60]

Non-CNS solid tumours

Minimal

479

1

1

555

1

1

High

47

1.30 [0.96–1.75]

1.84 [1.31–2.58]

23

1.49 [0.98–2.26]

1.79 [1.13–2.84]

  1. CNST: central nervous system tumour; HR: Hazard Ratio estimated with a Cox regression; 95%CI: 95% confidence interval
  2. 1Model adjusted for sex, birth year and year of entry
  3. 2Model adjusted for sex, birth year, year of entry, maternal age at birth, paternal and maternal occupational exposure to benzene, education level of the reference person in the household, SEP-index, degree of urbanization, residential exposure to background ionizing radiation, residential exposure to ambient NO2 (All variables assessed at entry into the cohort)