Fig. 1

Sulindac and Sulindac-PC are effective at reducing polyp burden. a Total intestinal polyp number by treatment group No Treatment (○), PBS (□), PC (∆), Sulindac (), Sulindac-PC (◊), groups with different letters are significantly different from each other. Each point represents data from an individual mouse. b Percent reduction in polyp count compared to No Treatment group. c Total intestinal polyp area by treatment group d Percent of polyps are shown by size category and treatment group, groups with different letters have significantly different proportions of 1.0–2.0 mm polyps. Columns = average, bars = standard error of the mean, N = 6–7 mice per treatment group, each symbol represents one mouse e Representative images of polyp annotations. Tissues are shown without (top) and with (bottom) polyps annotated (*). Arrow indicates a Peyer’s patch. Scale bar = 1000 μm