Table 1 Clinicopathological characteristics of the non-recurrent and recurrent groups

Median age (range)

67.5 (49–75)

71.5 (67–89)

0.069

Gender (male/female)

7/3

7/3

1.000

Smoking history (+/−)

7/3

6/4

1.000

Pathological stage (I/II)

10/0

5/5

0.033

Median tumor size (mm) (range)

23.5 (9–29)

24 (9–37)

0.649

Adenocarcinoma subtype

0.293

 Lepidic

2

0

 Papillary

5

7

 Acinar

1

2

 Solid

2

1

Lymph node metastasis (+/−)

0/10

5/5

0.033

Pleural invasion (+/−)

2/8

5/5

0.350

Lymphatic vessel invasion (+/−)

1/9

6/4

0.057

Blood vessel invasion (+/−)

2/8

9/1

0.005

Micropapillary component (+/−)

5/5

8/2

0.350

Spread through air space (+/−)

2/8

4/6

0.628

 EGFR (+/−)

2/8

6/4

0.170

 ALK (+/−)

0/8

0/7

–

Surgical procedure

1.000

 Lobectomy

10

9

 Wedge resection

0

1

Adjuvant chemotherapy

1.000

 Indication (Stage IA3-IIB)

8

9

 Received

4

4

Recurrent style

–

 Locoregional

–

3

 Distant

–

8