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Table 3 Predictors Of Survival

From: Outcomes of treatment with CHOP and EPOCH in patients with HIV associated NHL in a low resource setting

Variable

Univariable

Multivariable

CHR (95%CI)

P-Value

AHR (95%CI)

P-Value

Age in years

1.0 (0.98–1.05)

0.32

1.0 (0.96–1.04)

0.95

Sex: Male

1.2 (0.64–2.24)

0.57

1.6 (0.76–3.32)

0.22

Study arm: EPOCH

0.4 (0.10–1.78)

0.24

0.6 (0.13–2.84)

0.52

ECOG

 0–2

  3–4

3.4 (1.10–8.82)

0.01

1.7 (0.55–5.26)

0.36

  Not assessed

2.3 (1.01–5.05)

0.05

1.5 (0.60–3.80)

0.39

BMI

   < 18.5 Kg/m2

  18.5–24.9 kg/m2

0.4 (0.20–0.83)

0.01

0.4 (0.18–0.89)

0.03

   > 25 kg/m2

0.5 (0.23–1.33)

0.19

0.6 (0.21–2.02)

0.45

Lymphoma stage

 Early stage

  Late stage

1.8 (0.76–4.04)

0.19

1.6 (0.58–4.60)

0.35

  Not assessed

1.5 (0.49–4.32)

0.50

1 (0.28–3.94)

0.95

Type of lymphoma

 Diffuse large B-cell lymphoma

  Diffuse Large cell lymphoma

1.2 (0.58–2.63)

0.58

1.0 (0.39–2.43)

0.95

  Plasmablastic lymphoma

2.1 (0.58–7.75)

0.25

1.4 (0.30–6.02)

0.69

  NHL Other

2.5 (0.84–7.28)

0.10

1.7 (0.52–5.74)

0.37

  Burkitt’s

1.0 (0.12–7.45)

0.96

0.3 (0.03–3.45)

0.33

Presence of B-symptoms

0.9 (0.47–1.63)

0.67

0.9 (0.44–1.96)

0.85

Presence of comorbidity

0.7 (0.24–1.91)

0.46

0.9 (0.28–2.69)

0.81

Chemotherapy cycles received

  < 6

    

  > 6

0.2 (0.11–0.43)

< 0.001

0.2 (0.10–0.47)

< 0.001

  1. Note: AHR Adjusted Hazard Ratio, BMI Body Mass Index, CHR Crude Hazard Ratio, ECOG Eastern Cooperative Oncology Group