A | ||||
GO-BP Term | Enrichment Score | Count | % | P-Value |
positive regulation of transcription from RNA polymerase II promoter | 3.413985 | 22 | 12.22 | < 0.001 |
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 2.5522952 | 4 | 2.222 | 0.003 |
negative regulation of transcription from RNA polymerase II promoter | 2.4555568 | 16 | 8.889 | 0.004 |
transcription from RNA polymerase II promoter | 2.4471842 | 13 | 7.222 | 0.004 |
positive regulation of transcription, DNA-templated | 2.4336944 | 13 | 7.222 | 0.004 |
apoptotic process | 2.1092412 | 13 | 7.222 | 0.008 |
negative regulation of translational initiation | 2.064083 | 3 | 1.667 | 0.009 |
protein import into mitochondrial matrix | 1.95711 | 3 | 1.667 | 0.011 |
regulation of protein localization | 1.8821494 | 4 | 2.222 | 0.013 |
response to cytokine | 1.8821494 | 4 | 2.222 | 0.013 |
cellular response to cytokine stimulus | 1.7404426 | 3 | 1.667 | 0.018 |
cell morphogenesis | 1.6784701 | 4 | 2.222 | 0.021 |
positive regulation of mesenchymal cell proliferation | 1.6028585 | 3 | 1.667 | 0.025 |
intracellular protein transport | 1.6019839 | 7 | 3.889 | 0.025 |
protein sumoylation | 1.5991972 | 5 | 2.778 | 0.025 |
B | ||||
GO-CC Term | Enrichment Score | Count | % | P-Value |
cytosol | 4.721026 | 54 | 30 | < 0.001 |
nucleoplasm | 3.468485 | 44 | 24.44 | < 0.001 |
nucleus | 3.459493 | 72 | 40 | < 0.001 |
cytoplasm | 3.448156 | 70 | 38.89 | < 0.001 |
membrane | 2.786622 | 35 | 19.44 | 0.002 |
microtubule plus-end | 1.979181 | 3 | 1.667 | 0.01 |
PcG protein complex | 1.593489 | 3 | 1.667 | 0.025 |
nuclear chromatin | 1.476598 | 6 | 3.333 | 0.033 |
intracellular ribonucleoprotein complex | 1.428852 | 5 | 2.778 | 0.037 |
mitochondrial outer membrane | 1.3075 | 5 | 2.778 | 0.049 |
endoplasmic reticulum membrane | 1.253057 | 14 | 7.778 | 0.056 |
perinuclear region of cytoplasm | 1.207393 | 11 | 6.111 | 0.062 |
MLL5-L complex | 1.146143 | 2 | 1.111 | 0.071 |
mitochondrial inner membrane presequence translocase complex | 1.096965 | 2 | 1.111 | 0.08 |
C | ||||
GO-MF Term | Enrichment Score | Count | % | P-Value |
protein binding | 3.972219 | 109 | 60.56 | < 0.001 |
protein channel activity | 3.7469 | 4 | 2.222 | < 0.001 |
sequence-specific DNA binding | 3.320627 | 15 | 8.333 | < 0.001 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | 2.640286 | 11 | 6.111 | 0.002 |
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 2.106865 | 8 | 4.444 | 0.008 |
transcription factor activity, sequence-specific DNA binding | 1.648871 | 17 | 9.444 | 0.022 |
protein kinase activity | 1.643895 | 9 | 5 | 0.023 |
ATP binding | 1.307149 | 22 | 12.22 | 0.049 |
vascular endothelial growth factor receptor 2 binding | 1.25008 | 2 | 1.111 | 0.056 |
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | 1.197916 | 4 | 2.222 | 0.063 |
N6-methyladenosine-containing RNA binding | 1.185193 | 2 | 1.111 | 0.065 |
P-P-bond-hydrolysis-driven protein transmembrane transporter activity | 1.129258 | 2 | 1.111 | 0.074 |
poly(A) RNA binding | 1.119963 | 17 | 9.444 | 0.076 |
chromatin binding | 1.08038 | 8 | 4.444 | 0.083 |
mRNA 5′-UTR binding | 1.080159 | 2 | 1.111 | 0.083 |
D | ||||
KEGG pathway | Enrichment Score | Count | % | P-Value |
Pathways in cancer | 2.26453 | 11 | 6.111 | 0.005 |
PI3K-Akt signaling pathway | 2.145933 | 10 | 5.556 | 0.007 |
Oocyte meiosis | 1.604046 | 5 | 2.778 | 0.025 |
Pancreatic cancer | 1.566902 | 4 | 2.222 | 0.027 |
Platelet activation | 1.386975 | 5 | 2.778 | 0.041 |
Insulin signaling pathway | 1.307592 | 5 | 2.778 | 0.049 |
Proteoglycans in cancer | 1.304184 | 6 | 3.333 | 0.05 |
Focal adhesion | 1.259046 | 6 | 3.333 | 0.055 |
Rap1 signaling pathway | 1.229991 | 6 | 3.333 | 0.059 |
Hippo signaling pathway | 1.190921 | 5 | 2.778 | 0.064 |
MicroRNAs in cancer | 1.179653 | 7 | 3.889 | 0.066 |
HIF-1 signaling pathway | 1.146419 | 4 | 2.222 | 0.071 |
Vibrio cholerae infection | 1.020041 | 3 | 1.667 | 0.095 |