From: Long-term sexual functioning in germ-cell tumor survivors
 | All (%) | Treatment group | ||||
---|---|---|---|---|---|---|
 | AS | RT | CT | CTRT | P value | |
N = 170 (100%) (10)(((100) |  |  |  |  |  | |
Age (years) | ||||||
 Median (range) | 40 (21–77) |  |  |  |  |  |
Follow up (years) | ||||||
 Median (range) | 9 (5–32) |  |  |  |  |  |
Histology | ||||||
 Pure seminoma | 47 (28) | 8 | 11 | 19 | 9 | < 0.001 |
 Non-seminoma/mixed GCT | 116 (68) | 9 | 1 | 106 | 0 |  |
 Histology unknown | 7 (4) | 0 | 0 | 7 | 0 |  |
Primary tumor | ||||||
 Gonadal | 158 (92) | 17 | 12 | 120 | 9 | 0.39 |
 Primary retroperitoneal | 9 (6) | 0 | 0 | 9 | 0 |  |
 Primary mediastinal | 3 (2) | 0 | 0 | 3 | 0 |  |
IGCCCG risk group | ||||||
 Good risk | 77 (49) | 0 | 0 | 70 | 7 | 0.06 |
 Intermediate risk | 21 (12) | 0 | 0 | 21 | 1 |  |
 Poor risk | 29 (17) | 0 | 0 | 29 | 0 |  |
 unknown | 1 (0.5) | 0 | 0 | 1 | 0 |  |
Initial stage | ||||||
 I | 42 (26) | 17 | 12 | 11 | 2 | < 0.001 |
 I.S-III.A | 77 (45) | 0 | 0 | 70 | 7 |  |
 III.B | 21 (11) | 0 | 0 | 21 | 0 |  |
 III.C | 29 (18) | 0 | 0 | 29 | 0 |  |
 Stage unknown |  | 0 | 0 | 1 | 0 |  |
Treatment | ||||||
 AS | 17 (10) |  |  |  |  |  |
 RT only | 12 (7) |  |  |  |  |  |
  - adjuvant RT | 12(7) |  |  |  |  |  |
 CT only | 132 (78) |  |  |  |  |  |
  - 1st line only | 112 (65) |  |  |  |  |  |
  - more than 1st line | 20(12) |  |  |  |  |  |
 CTRT | 9 (5) |  |  |  |  |  |
  - 1st line treatment | 8 (4.5) |  |  |  |  |  |
  - 2nd line treatment | 1 (0.5)b |  |  |  |  |  |
Initial chemotherapy | ||||||
 BEPx3 | 43 (26) |  |  |  |  |  |
 EPx4 | 22 (13) |  |  |  |  |  |
 BEPx4 | 43 (25) |  |  |  |  |  |
 othera | 33 (19) |  |  |  |  |  |
Post-chemotherapy RPLND | ||||||
 no | 134 | 17 | 12 | 98 | 8 | 0.001 |
 yes | 35 | 0 | 0 | 34 | 1 |  |
Time from the end of treatment (years) | ||||||
 5–10 | 100 (59) | 15 | 8 | 70 | 7 | 0.01 |
 11–15 | 41 (24) | 1 | 4 | 35 | 1 |  |
 > 15 | 29 (17) | 1 | 0 | 27 | 1 |  |