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Table 3 Patients and tumor characteristics related to progression-free survival and overall survival according to multivariate analysis

From: Treatment strategy and outcomes in locally advanced head and neck squamous cell carcinoma: a nationwide retrospective cohort study (KCSG HN13–01)

Outcomes

 

Estimate (95% CI)

p-value

Progression-free survival

Hazard ratio

 

 Primary location (Others vs. Oropharynx)

3.65 (1.77–7.52)

< 0.001

 T classification (from one unit to next)

1.43 (1.09–1.89)

0.011

 Treatment strategy (Inadequate vs. CCRT)

2.28 (1.23–4.20)

0.009

Overall survival

 HPV status (Positive vs. Negative)

0.29 (0.14–0.63)

0.002

 Primary location (Oral cavity vs. Oropharynx)

1.82 (1.22–2.71)

0.003

 T classification (from one unit to next)

1.30 (1.08–1.57)

0.006

 N classification (from one unit to next)

1.58 (1.20–2.08)

0.001

 Treatment strategy (Inadequate vs. CCRT)

2.31 (1.35–3.97)

0.002

  1. CCRT Concurrent chemoradiotherapy, HPV Human papillomavirus