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Fig. 3 | BMC Cancer

Fig. 3

From: An integrative pan-cancer investigation reveals common genetic and transcriptional alterations of AMPK pathway genes as important predictors of clinical outcomes across major cancer types

Fig. 3

The 24-AMPK-gene set is independent of tumor stage and histological subtype. a Kaplan-Meier analyses of patients grouped by tumor, node and metastasis (TNM) stage (breast and stomach cancers) or by the histological subtype of leiomyosarcoma and the 24-gene score. For leiomyosarcoma, the log-rank test reveals a significant difference in survival rates between 1st and 4th quartile patients. b Receiver-operating characteristic (ROC) analyses on the 5-year predictive performance of the 24-gene set. ROC curves generated by the 24-gene set are compared to curves generated from both 24-gene set and TNM staging, where available, or histological subtype. AUC: area under the curve

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