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Table 2 Histopathological changes of patients with CRCLM after NC

From: Quantified MRI and 25OH-VitD3 can be used as effective biomarkers for patients with neoadjuvant chemotherapy-induced liver injury in CRCLM?

2A Histopathological features Value Percentage (%)
Hepatocellular ballooning 31 75.6
Focal or bridging necrosis 28 68.9
Eosinophilic infiltration 29 71.1
Bile ducts damage 22 53.3
Hepatic sinus widening 15 37.8
Kupper hyperplasia 10 24.4
Collagen accumulation 2 4.44
Clastic necrosis in the portal area 2 4.44
2B His-Scores Grade 0 Grade 1 Grade2 Grade 3
CASH* 8 (19.5%) 22 (53.7%) 11 (26.8%)
SOS* 10 (24.4%) 23 (56.1%) 8 (9.76%)
CASH & SOS 7 (17.1%) 23 (56.1%) 11 (26.8%)
  1. *CASH, nonalcoholic steatohepatitis, SOS sinusoidal obstruction syndrome