Table 1 Comparison of clinicopathological characteristics before and after PSM in surgical group
Patient Characteristics | Unmatched comparison | Matched comparison | ||||
|---|---|---|---|---|---|---|
Patients with NEC components (n = 117) | Gastric adenocarcinoma (n = 308) | P value | Patients with NEC components (n = 88) | Gastric adenocarcinoma (n = 128) | P value | |
Age (year), mean ± SD | 61.7 ± 9.4 | 55.2 ± 10.8 | < 0.001 | 59.7 ± 9.4 | 58.9 ± 9.7 | 0.551 |
Gender (male/female) | 100/17 | 282/26 | 0.063 | 76/12 | 112/16 | 0.807 |
BMI, mean ± SD | 24.1 ± 3.1 | 23.6 ± 3.6 | 0.100 | 24.4 ± 3.1 | 23.8 ± 3.6 | 0.182 |
Adjuvant therapy | < 0.001 | 0.189 | ||||
Yes | 87 (74.4) | 109 (35.4) | 58 (65.9) | 73 (57.0) | ||
No | 30 (25.6) | 199 (64.6) | 30 (34.1) | 55 (43.0) | ||
Tumor location | < 0.001 | 0.679 | ||||
Upper third | 70 (59.8) | 74 (24.0) | 46 (52.3) | 60 (46.9) | ||
Middle third | 18 (15.4) | 41 (13.3) | 14 (15.9) | 19 (14.8) | ||
Lower third | 28 (23.9) | 192 (62.3) | 28 (31.8) | 48 (37.5) | ||
Entire | 1 (0.9) | 1 (0.3) | 0 (0.0) | 1 (0.8) | ||
Tumor size | 0.023 | 0.669 | ||||
< 5 cm | 80 (68.4) | 243 (78.9) | 63 (71.6) | 95 (74.2) | ||
≥ 5 cm | 37 (31.6) | 65 (21.1) | 25 (28.4) | 33 (25.8) | ||
Type of gastrectomy | < 0.001 | 0.077 | ||||
Total gastrectomy | 78 (66.7) | 79 (25.6) | 53 (60.2) | 59 (46.1) | ||
Distal gastrectomy | 29 (24.8) | 206 (66.9) | 29 (33.0) | 51 (39.8) | ||
Proximal gastrectomy | 10 (8.5) | 23 (7.5) | 6 (6.8) | 18 (14.1) | ||
Surgical procedure | < 0.001 | 0.001 | ||||
Open | 106 (90.6) | 212 (68.6) | 80 (90.9) | 92 (71.9) | ||
Laparoscopic | 11 (9.4) | 96 (32.2) | 8 (9.1) | 36 (28.1) | ||
T stage | < 0.001 | < 0.001 | ||||
T1 | 16 (13.7) | 195 (63.3) | 14 (15.9) | 53 (41.4) | ||
T2 | 26 (22.2) | 18 (5.8) | 25 (28.4) | 12 (9.4) | ||
T3 | 48 (41.0) | 49 (15.9) | 27 (30.7) | 35 (27.3) | ||
T4 | 27 (23.1) | 46 (14.9) | 22 (25.0) | 28 (21.9) | ||
N stage | < 0.001 | 0.428 | ||||
N0 | 48 (41.0) | 210 (68.2) | 37 (42.0) | 62 (48.4) | ||
N1 | 32 (27.4) | 26 (8.4) | 22 (25.0) | 22 (17.2) | ||
N2 | 20 (17.1) | 27 (8.8) | 16 (18.2) | 16 (18.2) | ||
N3 | 17 (14.5) | 45 (14.6) | 13 (14.8) | 24 (18.8) | ||
M stage | 0.216 | 0.406 | ||||
M0 | 117 (100.0) | 304 (98.7) | 88 (100.0) | 127 (99.2) | ||
M1 | 0 (0.0) | 4 (1.3) | 0 (0.0) | 1 (0.8) | ||
pTNM stage | < 0.001 | 0.399 | ||||
I | 30 (25.6) | 202 (65.6) | 30 (34.1) | 56 (43.8) | ||
II | 47 (40.2) | 32 (10.4) | 26 (29.5) | 30 (23.4) | ||
III | 40 (34.2) | 70 (22.7) | 32 (36.4) | 41 (32.0) | ||
IV | 0 (0.0) | 4 (1.3) | 0 (0.0) | 1 (0.8) | ||