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Fig. 3 | BMC Cancer

Fig. 3

From: SNHG17 drives malignant behaviors in astrocytoma by targeting miR-876-5p/ERLIN2 axis

Fig. 3

ERLIN2 worked as the downstream target of miR-876-5p and contributed to the progression of astrocytoma (a) RT-qPCR assays were carried out to measure mRNAs expressions in cells transfected with miR-876-5p mimics. b ERLIN2 expression was evaluated in astrocytoma cell lines. c MiR-876-5p expression was examined in cells received miR-876-5p inhibitor. d-e ERLIN2 expression was assessed in cells transfected with miR-876-5p inhibitor and sh-SNHG17#1/2. f The binding sequences between ERLIN2 and miR-876-5p were predicted by starBase. g RNA pull down certified miR-876-5p bound to ERLIN2. h RIP validated that SNHG17, miR-876-5p and ERLIN2 coexisted in RNA induced silencing complexes (RISCs). i Luciferase reporter assays verified that ERLIN2 bound to miR-876-5p. **P < 0.01

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