Table 1 Correlation between OTX1 expression and Clinicopathologic Variables of LSCC patients
OTX1 | ||||
|---|---|---|---|---|
Variables | Cases (n = 99) | Low expression (n = 29) | High expression (n = 70) | P |
Age (years) | ||||
≤ 60 | 47 | 15 (66.9%) | 32 (33.1%) | |
> 60 | 52 | 14 (61.4%) | 38 (38.6%) | 0.586 |
Sex | ||||
Male | 95 | 27 (63.5%) | 68 (36.5%) | |
Female | 4 | 2 (87.5%) | 2 (12.5%) | 0.353 |
Smoking history | ||||
Yes | 86 | 29 (64.0%) | 57 (36.0%) | |
No | 13 | 0 (64.5%) | 13 (35.5%) | 0.013 |
Drinking history | ||||
Yes | 31 | 12 (62.5%) | 19 (37.5%) | |
No | 68 | 17 (64.7%) | 51 (35.3%) | 0.165 |
T classification | ||||
T1-T2 | 58 | 21 (69.0%) | 37 (31.0%) | |
T3-T4 | 41 | 8 (55.7%) | 33 (44.3%) | 0.072 |
Lymph node metastasis | ||||
Negative | 75 | 26 (65.5%) | 49 (34.5%) | |
Positive | 24 | 3 (57.7%) | 21 (42.3%) | 0.038 |
Histological grade | ||||
Well | 39 | 14 (66.1%) | 25 (33.9%) | |
Moderately | 44 | 11 (63.2%) | 33 (36.8%) | |
Poorly | 16 | 4 (61.4%) | 12 (38.6%) | 0.508 |
Primary location | ||||
Supraglottic | 22 | 4 (65.4%) | 18 (34.6%) | |
Glottic | 70 | 21 (55.3%) | 49 (44.7%) | |
Subglottic | 7 | 4 (58.3%) | 3 (41.7%) | 0.139 |