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Table 1 Characteristics of patients according to the 2015 ATA risk-stratification system in the postoperative setting

From: Tumor burden of persistent disease in patients with differentiated thyroid cancer: correlation with postoperative risk-stratification and impact on outcome

 

LR

(n = 395)

IR

(n = 202)

HR

(n = 21)

p

Mean age ± SD (yrs)

49 ± 15

51 ± 18

67 ± 10

<.0001

Sex ratio (Female)

3.8 (79%)

2.0 (67%)

2.5 (71%)

0.005

Mean tumor size ± SD (mm)

22 ± 15

25 ± 18

51 ± 34

<.0001

Histology

  

 PTC

348 (88%)

169 (84%)

11 (52%)

<.0001

 FTC

47 (12%)

12 (6%)

4 (19%)

 

 PDTC

0

21 (10%)

6 (29%)

 

Aggressive pathological subtypes

 

<.001

 No

395 (100%)

172 (85%)

18 (86%)

 

 Yes

0

30 (15%)

3 (14%)

 

Extra-thyroidal extension

 

<.0001

 Minimal

0

91 (45%)

1 (5%)

 

 Gross

0

0

14 (67%)

 

T status (TNM 2017)

 

<.0001

 T1a + T1b

230 (58%)

112 (56%)

1 (5%)

 

 T2

152 (39%)

57 (28%)

4 (19%)

 

 T3a + T3b

13 (3%)

33 (16%)

2 (9%)

 

 T4a + T4b

0

0

14 (67%)

 

N status (TNM 2017)

 

<.0001

 Nx

249 (63%)

31 (15%)

6 (28%)

 

 N0

119 (30%)

27 (13%)

5 (24%)

 

 N1a + N1b

27 (7%)

144 (72%)

10 (48%)

 

M status (TNM 2017)

 

<.0001

 M0

395 (100%)

202 (100%)

10 (48%)

 

 M1

0

0

11 (52%)

 

Positive TgAb level

48 (12%)

32 (16%)

2 (10%)

0.43

Stimulated Tg level at RAI treatment (range)a

1.9 (0.1–744.0)

6.4 (0.1–4340.0)

126.2 (0.4–58,690.0)

<.0001

  1. aIn patients without positive TgAb level