Table 3 Multivariate analysis of risk factors for LRR and DM in 1521 patients without PMRT

Age (≤40 vs. >40)

1.75 (1.16–2.66)

.008

1.69 (1.21–2.36)

0.002

Tumor location (inner quadrant vs. non-inner quadrant)

1.92 (1.32–2.79)

.001

1.48 (1.09–2.01)

0.012

Positive lymph node (2–3 vs. 1)

1.73 (1.21–2.47)

.003

Lympho-vascular invasion (yes vs. no)

1.44 (0.97–2.16)

0.074

 Ia

Reference

Reference

 Ib-IIa

2.10 (1.23–3.56)

.006

1.45 (1.01–2.08)

0.044

 IIb-IIIa

5.95 (3.46–10.24)

< .001

3.34 (2.26–4.93)

<  0.001