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Table 1 Baseline characteristics of 1986 patients with breast cancer

From: Effectiveness of the AJCC 8th edition staging system for selecting patients with T1–2N1 breast cancer for post-mastectomy radiotherapy: a joint analysis of 1986 patients from two institutions

 

No. (%)

No PMRT

(n = 1521)

PMRT

(n = 465)

p

Entire Cohort

(N = 1986)

Treatment era

   

<  0.001

 1/2000–12/2009

959 (48.3)

807 (53.1)

152 (32.7)

 

 1/2010–12/2014

1027 (51.7)

714 (46.9)

313 (67.3)

 

Age (years)

   

<  0.001

  ≤ 40

349 (17.7)

221 (14.5)

128 (27.5)

 

  > 40

1637 (82.3)

1300 (85.5)

337 (72.5)

 

Tumor location

   

0.249

 Inner quadrant

439 (22.1)

346 (22.7)

93 (20.0)

 

 Other quadrants

1526 (76.8)

1162 (76.4)

364 (78.3)

 

 Unknown

21 (1.1)

13 (0.9)

8 (1.7)

 

Stage (AJCC 8th ed.)

   

<  0.001

 IA

621 (31.3)

508 (33.4)

113 (24.3)

 

 IB- IIA

985 (49.6)

760 (50.0)

225 (48.4)

 

 IIB- IIIA

380 (19.1)

253 (16.6)

127 (27.3)

 

No. of positive nodes

   

<  0.001

 1

1023 (51.5)

878 (57.7)

145 (31.2)

 

 2–3

963 (48.5)

643 (42.3)

320 (68.8)

 

No. of nodes dissected

   

0.002

  < 10

124 (6.2)

80 (5.3)

44 (9.5)

 

  ≥ 10

1862 (93.8)

1441 (94.7)

421 (90.5)

 

Lympho-vascular invasion

   

<  0.001

 Yes

279 (14.0)

184 (12.1)

95 (20.4)

 

 No

1704 (85.8)

1337 (87.9)

367 (78.9)

 

 Unknown

3 (0.2)

0 (0)

3 (0.7)

 

Histological grade

   

0.004

 I

76 (3.8)

69 (4.5)

7 (1.5)

 

 II

1309 (65.9)

1008 (66.3)

301 (64.7)

 

 III

601 (30.3)

444 (29.2)

157 (33.8)

 

T stage

   

0.001

 T1

953 (48.0)

762 (50.1)

191 (41.1)

 

 T2

1033 (52.0)

759 (49.9)

274 (58.9)

 

Estrogen receptor

   

<  0.001

 Negative

509 (25.6)

358 (23.5)

151 (32.5)

 

 Positive

1477 (74.4)

1163 (76.5)

314 (67.5)

 

Progesterone receptor

   

<  0.001

 Negative

542 (27.6)

369 (24.3)

173 (37.2)

 

 Positive

1444 (72.4)

1152 (75.7)

292 (62.8)

 

HER2 status

   

0.002

 Negative

1804 (90.8)

1410 (92.7)

394 (84.7)

 

 Positive

182 (9.2)

111 (7.2)

71 (15.3)

 
  1. Abbreviations: PMRT post-mastectomy radiotherapy, AJCC 8th ed. American Joint Committee on Cancer Staging Manual, 8th edition