Establishment of multifactor predictive models for the occurrence and progression of cervical intraepithelial neoplasia

Table 2 The clinical features and genes expressed in the CIN and normal groups

	normal	CIN	Z/X²	P
age	44.08 ± 10.00	41.71 ± 9.31	−1.480	0.139
gravidity	3.00 ± 1.76	3.46 ± 1.84	−1.536	0.124
parity	1.66 ± 0.85	1.67 ± 1.34	−0.561	0.561
HPV infection			26.552	0.000
positive	15	47
negative	23	5
menopause
yes	9	9	0.558	0.455
no	29	43
TCT
CINII-(Normal/ASCUS)	28	10	/	0.000
CINII+(LSIL/HSIL/SCC)	16	36
CTNNB1	0.85 ± 0.15	0.88 ± 0.24	−1.626	0.104
TGFBR2	1613.35 ± 369.73	665.56 ± 357.49	−2.916	0.004
FOXO1	0.04 ± 0.01	0.50 ± 0.30	−2.728	0.006
PRKCI	0.65 ± 0.22	0.56 ± 0.11	−1.675	0.094
CSKN1A1	211.45 ± 120.00	135.69 ± 81.39	−0.270	0.787
TP73	150.80 ± 44.11	75.39 ± 21.31	−1.805	0.071
MUC2	0.92 ± 0.25	1.89 ± 1.26	−0.343	0.732
PIK3CA	4.91 ± 0.87	7.28 ± 1.98	−1.005	0.315
CCND2	0.47 ± 0.19	1.40 ± 0.72	−0.556	0.579
CTPB2	40.18 ± 11.28	16.59 ± 6.14	−2.091	0.037

ISSN: 1471-2407