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Table 3 Univariate and multivariate analysis of DFS in fertility desiring patients after fertility-sparing surgery

From: Staging procedures fail to benefit women with borderline ovarian tumours who want to preserve fertility: a retrospective analysis of 448 cases

 

Univariate

P Value

Multivariate

P Value

OR

95% confidence interval

OR

95%

confidence interval

FIGO Stage

 I

1

     

 ≧II

21.061

9.662–45.909

0.000

11.586

4.535–29.602

0.000

Histology

 Serous

1

 

0.010

  

0.155

 Mucinous

0.196

0.068–0.654

0.003

  

0.189

 Others

0.000

 

0.975

  

NA

Lesion lateral

 Unilateral

1

     

 Bilateral

5.491

2.570–11.73

0.000

2.581

1.061–6.283

0.037

Micropapillary

 Yes

1.976

0.840–4.649

0.119

  

NA

 No

1

     

Microinvasion

 Yes

14.644

6.940–30.903

0.000

  

0.955

 No

1

     

Carcinogenesis

 Yes

0.609

0.083–4.483

0.626

  

NA

 No

1

     

Staging surgery

 Yes

4.290

1.979–9.298

0.000

  

0.358

 No

1

     

Adjuvant chemotherapy

 Yes

7.797

3.648–16.664

0.000

  

0.391

 No

1

     

Ascites/Pelivic washings

 Positive

13.350

5.612–31.770

0.000

  

0.888

 Negative

1

     

Surgical Approach

 Laparotomy

1

     

 Laparoscopy

0.332

0.135–0.820

0.017

0.367

0.148–0.913

0.031

CA-125

 Normal

1

     

 Elevated

1.649

0.748–3.632

0.215

  

NA

Fertility sparing surgery

 Cystectomy-included

1

     

 Adnexectomy

0.382

0.168–0.867

0.021

0.367

0.148–0.913

0.014

Appendectomy

 No

1

     

 Yes

0.240

0.083–0.692

0.008

  

0.189

Invasive implants

 No

1

     

 Yes

14.289

6.400–31.902

0.000

4.832

1.663–14.037

0.004