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Table 3 Multivariate analysis for overall survival

From: Log odds of positive lymph nodes is prognostically equivalent to lymph node ratio in non-metastatic colon cancer

Variable Multivariate analysis
HR (95% CI) p - value HR (95% CI) p - value
1st episode (n = 856)
Sex Male   
Female   
Age (yrs) < 60   
60–79   
80+ 6.208 (2.204, 17.484) < 0.001   
All episodes (n = 862) LNR   LODDS  
Tumour site Caecum   
Ascending colon    
Hepatic flexure 0.212 (0.046, 0.980) 0.047 0.200 (0.043, 0.922) 0.039
Transverse colon   
Splenic flexure   
Descending colon   
Sigmoid colon 0.092 (0.020, 0.421) 0.002 0.079 (0.017, 0.368) 0.001
Rectosigmoid   
T stage 0–2    
3    
4 8.92 (3.520, 22.605) < 0.001 8.57 (3.394, 21.655) < 0.001
N stage 0   -*   -*
1   -*   -*
2   -*   -*
ASA 1   -*   -*
2   -*   -*
3   -*   -*
4   -*   -*
Pathological grade Undifferentiated   
Poor differentiation    
Moderate differentiation   
Well differentiated   
LVI No   
Yes   
CRM Negative > 1 mm   
Positive ≤1 mm   
Not reported   
≥12 LNY No   
Yes 0.423 (0.220, 0.813) 0.010 0.382 (0.199, 0.734) 0.004
  1. ASA American Society of Anesthesiologists, CI Confidence interval, CRM Circumferential margin, LNR Lymph node ratio, LNY Lymph node yield, LODDS Log odds of positive lymph nodes, LVI Lymphovascular invasion.
  2. * omitted due to collinearity