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Table 2 Univariate analysis for overall survival

From: Log odds of positive lymph nodes is prognostically equivalent to lymph node ratio in non-metastatic colon cancer

Variable Univariate analysis
HR (95% CI) p-value
1st episode (n = 856)
Sex Male Reference group  
Female 0.788 (0.466, 1.332) 0.37
Age (yrs) < 60 Reference group  
60–79 1.462 (0.492, 4.345) 0.494
80+ 6.129 (2.177, 17.257) < 0.001
All episodes (n = 862)
Tumour site Caecum Reference group  
Ascending colon 0.961 (0.484, 1.908) 0.910
Hepatic flexure 0.372 (0.085, 1.627) 0.189
Transverse colon 0.757 (0.340, 1.686) 0.495
Splenic flexure 0.450 (0.103, 1.968) 0.289
Descending colon 0.596 (0.136, 2.607) 0.492
Sigmoid colon 0.080 (0.018, 0.350) < 0.001
Rectosigmoid 0.534 (0.194, 1.469) 0.224
T stage 0–2 Reference group  
3 2.501 (1.221, 5.123) 0.012
4 10.032 (4.529, 22.221) < 0.001
N stage 0 Reference group  
1 0.878 (0.408, 1.891) 0.740
2 2.852 (1.483, 5.487) 0.002
ASA 1 Reference group  
2 3.843 (0.884, 16.715) 0.073
3 8.702 (2.059, 36.767) 0.003
4 30.668 (6.918, 135.948) < 0.001
Pathological grade Undifferentiated < 0.001 (< 0.001, < 0.001) 0.996
Poor differentiation 2.43 (1.415, 4.168) 0.001
Moderate differentiation Reference group  
Well differentiated 0.515 (0.070, 3.776) 0.514
LVI No Reference group  
Yes 1.916 (1.124, 3.264) 0.017
CRM Negative > 1 mm Reference group  
Positive ≤1 mm 2.838 (0.382, 21.084) 0.31
Not reported 0.764 (0.441, 1.322) 0.34
  ≥ 12 LNY No Reference group  
Yes 0.803 (0.449, 1.435) 0.46
LNR groups < 0.05 Reference group  
0.05 to < 0.2 0.732 (0.287, 1.867) 0.51
≥ 0.2 3.775 (2.063, 6.908) < 0.001
LODDS <−1.36 Reference group  
−1.36 to −0.53 0.852 (0.428, 1.695) 0.65
> 0.53 3.715 (1.974, 6.991) < 0.001
  1. ASA American Society of Anesthesiologists, CI Confidence interval, CRM Circumferential margin, LNR Lymph node ratio, LNY Lymph node yield, LODDS Log odds of positive lymph nodes, LVI Lymphovascular invasion.
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