Table 1 Demographics and baseline characteristics (ASaT population)
Fosaprepitant regimen | Control regimen | |||||||
|---|---|---|---|---|---|---|---|---|
GI or colorectal cancers (n = 135) | Lung cancer (n = 130) | Breast cancer (n = 110) | Gynecologic cancer (n = 81) | GI or colorectal cancers (n = 132) | Lung cancer (n = 124) | Breast cancer (n = 121) | Gynecologic cancer (n = 71) | |
Age, years | ||||||||
Median (range) | 62 (24–85) | 65 (36–82) | 57 (28–78) | 58 (31–88) | 60 (23–88) | 65 (38–82) | 54 (28–81) | 56 (24–78) |
Age group, n (%) | ||||||||
< 50 years | 21 (15.6) | 7 (5.4) | 37 (33.6) | 25 (30.9) | 21 (15.9) | 5 (4.0) | 39 (32.2) | 24 (33.8) |
≥ 50 years | 114 (84.4) | 123 (94.6) | 73 (66.4) | 56 (69.1) | 111 (84.1) | 119 (96.0) | 82 (67.8) | 47 (66.2) |
Sex, n (%) | ||||||||
Male | 86 (63.7) | 90 (69.2) | 1 (0.9) | 0 | 76 (57.6) | 90 (72.4) | 0 | 0 |
Female | 49 (36.3) | 40 (30.8) | 109 (99.1) | 81 (100) | 56 (42.4) | 34 (27.4) | 121 (100) | 71 (100) |
History of motion sickness, n (%) | 8 (5.9) | 5 (3.8) | 5 (4.5) | 8 (9.9) | 3 (2.3) | 4 (3.2) | 12 (9.9) | 9 (12.7) |
History of emesis during pregnancy, n (%) | 11 (8.1) | 7 (5.4) | 24 (21.8) | 15 (18.5) | 15 (11.4) | 6 (4.8) | 23 (19.0) | 15 (21.1) |
History of alcohol use, n (%) | 69 (51.1) | 68 (52.3) | 35 (31.8) | 30 (37.0) | 58 (43.9) | 67 (54.0) | 41 (33.9) | 21 (29.6) |
Chemotherapy regimen, n (%)a | n = 135 | n = 129 | n = 110 | n = 81 | n = 132 | n = 125 | n = 121 | n = 71 |
Single day | 28 (20.7) | 108 (83.7) | 100 (90.9) | 81 (100) | 21 (15.9) | 109 (87.2) | 110 (90.9) | 69 (97.2) |
Multiple day | 105 (77.8) | 18 (14.0) | 0 | 0 | 109 (82.6) | 14 (11.2) | 0 | 2 (2.8) |