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Table 1 Patients’ Demographic and Clinical Characteristics, Tumor Features, and Outcome

From: Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma

Gender (M:F)

15:5

Age (years)

73 [62–77]

HBV positivity (%)

1 (5%)

HCV positivity (%)

6 (30%)

NASH (%)

3 (15%)

Alcohol abuse (%)

7 (35%)

MELD score

7 [6–10]

AFP, (ng/mL)

7.5 [3.2–23.5]

CEA, (ng/mL)

1.7 [1.1–3.3]

CA 19.9 (UI/mL)

16.9 [9.9–19.3]

Tumor number (%)

 

- 1

14 (70%)

- 2

4 (20%)

- 3

2 (10%)

Satellites lesions (%)

3 (15%)

Tumor max diameter (cm)

4.3 [3–10.8]

Edmonson-Steiner grading (%)

 - G1

4 (20%)

 - G2

12 (60%)

 - G3

4 (20%)

Microvascular invasion (%)

7 (35%)

Tumor staging (%)

 - T1

7 (35%)

 - T2

7 (35%)

 - T3

3 (15%)

 - T4

3 (15%)

Tumor recurrence (%)

10 (50%)

Recurrence time, (months)

25.4 [7.4–33.5]

  1. Continuous variables are expressed by median [interquartile range], Categorical variables by percentage
  2. AFP alphafetoprotein; CA 19.9 Carbohydrate Antigen 19.9, CEA carcinoembryonic antigen, HBV hepatitis B virus, HCV hepatitis C virus, NASH non alcoholic steatohepatitis, MELD Model for end-stage liver disease