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Fig. 3 | BMC Cancer

Fig. 3

From: Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma

Fig. 3

Effect of APE1 silencing on mitochondrial respiratory parameters. a Profiles of mitochondria bioenergetics measurements measured with Seahorse. Time and type of stressor administration are indicated. b The graph displays the relative average (±SD) basal and maximal respiration, as well as ATP production of HeLa clones silenced for APE1 expression (shRNA) and after re-expression of APE1 in all cells (APE1 WT) or only into the mitochondrial matrix (MTS-APE1). Data reported are the mean of four independent biological replicates. (*: p < 0.05; **: p < 0.01)

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BMC Cancer

ISSN: 1471-2407

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