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Table 3 Univariate analysis of prognostic factors for overall survival (OS) and disease-free survival (DFS) in matched cohort

From: Influence of tumor location on short- and long-term outcomes after laparoscopic surgery for rectal cancer: a propensity score matched cohort study

Variables Numbers 5-year OS (%) P value 5-year DFS (%) P value
Sex
 Male 104 83.4 0.607 84.4 0.057
 Female 94 79.4 72.4
Age(y)
 ≤60 112 89.7 0.001 84.8 0.010
 >60 86 71.3 70.3
ASA
 I 102 84.9 0.293 84.4 0.036
 II- III 96 78.3 72.3
BMI (kg/m2)
 <25 107 77.3 0.074 79.7 0.986
 ≥25 91 86.7 77.7
Location
 Mid/high 99 86.4 0.033 86.2 0.017
 Low 99 77.0 71.2
Preoperative CEA (ng/ml)
 ≤5 137 82.6 0.043 82.2 0.141
 >5 61 79.1 71.4
Preoperative CA19–9 (U/ml)
 ≤37 180 84.0 0.006 80.6 0.019
 >37 18 58.8 60.2
Preoperative CA72.4 (U/ml)
 ≤6.7 175 82.2 0.543 79.1 0.436
 >6.7 23 78.0 75.6
Tumor differentiation
 Well/moderate 159 84.3 0.079 79.1 0.915
 Poor 39 71.0 76.9
Pathological T stage
 pT0–2 73 92.0 0.008 85.2 0.288
 pT3–4 125 75.6 74.7
Pathological N stage
 pN0 98 94.2 <0.001 86.0 0.026
 pN1–2 100 68.9 71.2
Lymphovascular invasion
 Negative 174 86.7 <0.001 80.3 0.118
 Positive 24 46.7 65.5
Perineural invasion
 Negative 195 82.0 0.192 79.0 0.200
 Positive 3 50.0 50.0
Type of operation
 Restorative 127 86.2 0.225 81.3 0.235
 Non-restorative 71 73.5 73.8
Harvested lymph nodes
 ≥12 139 82.4 0.632 82.6 0.018
 <12 59 80.2 69.6
Distal resection margin (cm)
 ≥1 187 81.7 0.871 77.5 0.096
 <1 11 80.8 100.0
CRM (mm)
 >1 192 81.7 0.310 80.2 <0.001
 ≤1 6 80.0 33.3
Operative complications
 No 174 84.8 0.003 79.7 0.569
 Yes 24 59.5 71.9
Reoperation
 No 193 82.3 0.121 78.1 0.263
 Yes 5 60.0 100.0
Neoadjuvant therapy
 No 143 82.4 0.519 81.9 0.035
 Yes 55 80.2 70.2
Adjuvant chemotherapy
 No 82 79.2 0.882 82.4 0.310
 Yes 116 83.3 76.2
  1. ASA American Society of Anesthesiologists, BMI Body mass index, CEA Carcinoembryonic antigen, CRM Circumferential resection margin