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Table 2 Perioperative outcomes and recurrence according to tumor location: overall cohort and matched cohort

From: Influence of tumor location on short- and long-term outcomes after laparoscopic surgery for rectal cancer: a propensity score matched cohort study

Variables Overall patients Matched patients
LRC (n = 138) M/HRC (n = 235) P value LRC (n = 99) M/HRC (n = 99) P value
Type of operation, n (%)    <0.001    <0.001
 Restorative 41 (29.7) 228 (97.0)   32 (32.3) 95 (96.0)  
 Non-restorative 97 (70.3) 7 (3.0)   67 (67.7) 4 (4.0)  
Operation time (range) (min) 231 (136–468) 182 (77–375) <0.001 231 (136–435) 200 (77–375) <0.001
Blood loss (range) (ml) 50 (10–300) 50 (5–2000) <0.001 50 (10–300) 50 (5–600) 0.015
Protective ostomy in LAR, n (%) 36/41 (87.8) 106/228 (46.5) <0.001 28/32 (87.5) 52/95 (54.7) 0.001
Harvested lymph nodes, n (%)    <0.001    0.437
 <12 55 (39.9) 49 (20.9)   32 (32.3) 27 (27.3)  
 ≥12 83 (60.1) 186 (79.1)   67 (67.7) 72 (72.7)  
Distal resection margin (cm), n (%)    0.616    0.756
 <1 6 (4.3) 13 (5.5)   5 (5.1) 6 (6.1)  
 ≥ 1 132 (95.7) 222 (94.5)   94 (94.9) 93 (93.9)  
Positive CRM, n (%) 4 (2.9) 3 (1.3) 0.431 3 (3.0) 3 (3.0) 1.000
Conversions, n (%) 2 (1.4) 8 (3.4) 0.334 1 (1.0) 4 (4.0) 0.369
Operative complications, n (%) 24 (17.4) 24 (10.2) 0.046 16 (16.2) 8 (8.1) 0.082
Reoperation, n (%) 6 (4.3) 3 (1.3) 0.082 4 (4.0) 1 (1.0) 0.369
Postoperative LOS (range) (days) 9 (5–26) 9 (3–33) 0.172 9 (5–26) 8 (3–33) 0.011
30-day mortality, n (%) 0 (0) 0 (0) 1.000 0 (0) 0 (0) 1.000
Recurrence, n (%) 35 (25.4)a 34 (14.5)b 0.009 28 (28.3)a 14 (14.1)b 0.015
 Local recurrence 9 (6.5) 4 (1.7) 0.019 9 (9.1) 4 (4.0) 0.251
 Distant metastasis 28 (20.3) 32 (13.6) 0.090 21 (21.2) 12 (12.1) 0.086
  Lung 7 (5.1) 10 (4.3) 0.715 6 (6.1) 5 (5.1) 0.756
  Liver 1 (0.7) 6 (2.6) 0.267 1 (1.0) 2 (2.0) 1.000
  Other site 6 (4.3) 4 (1.7) 0.182 3 (3.0) 1 (1.0) 0.621
  Multiple organs 14 (10.1) 12 (5.1) 0.065 11 (11.1) 4 (4.0) 0.104
  1. LRC Low rectal cancer, M/HRC Mid/high rectal cancer, LAR Low anterior resection, CRM Circumferential resection margin, LOS Length of stay
  2. a/b Local recurrence and distant metastasis occurred synchronously in 2 cases both in LRC and M/HRC groups