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Table 2 Perioperative outcomes and recurrence according to tumor location: overall cohort and matched cohort

From: Influence of tumor location on short- and long-term outcomes after laparoscopic surgery for rectal cancer: a propensity score matched cohort study

Variables

Overall patients

Matched patients

LRC (n = 138)

M/HRC (n = 235)

P value

LRC (n = 99)

M/HRC (n = 99)

P value

Type of operation, n (%)

  

<0.001

  

<0.001

 Restorative

41 (29.7)

228 (97.0)

 

32 (32.3)

95 (96.0)

 

 Non-restorative

97 (70.3)

7 (3.0)

 

67 (67.7)

4 (4.0)

 

Operation time (range) (min)

231 (136–468)

182 (77–375)

<0.001

231 (136–435)

200 (77–375)

<0.001

Blood loss (range) (ml)

50 (10–300)

50 (5–2000)

<0.001

50 (10–300)

50 (5–600)

0.015

Protective ostomy in LAR, n (%)

36/41 (87.8)

106/228 (46.5)

<0.001

28/32 (87.5)

52/95 (54.7)

0.001

Harvested lymph nodes, n (%)

  

<0.001

  

0.437

 <12

55 (39.9)

49 (20.9)

 

32 (32.3)

27 (27.3)

 

 ≥12

83 (60.1)

186 (79.1)

 

67 (67.7)

72 (72.7)

 

Distal resection margin (cm), n (%)

  

0.616

  

0.756

 <1

6 (4.3)

13 (5.5)

 

5 (5.1)

6 (6.1)

 

 ≥ 1

132 (95.7)

222 (94.5)

 

94 (94.9)

93 (93.9)

 

Positive CRM, n (%)

4 (2.9)

3 (1.3)

0.431

3 (3.0)

3 (3.0)

1.000

Conversions, n (%)

2 (1.4)

8 (3.4)

0.334

1 (1.0)

4 (4.0)

0.369

Operative complications, n (%)

24 (17.4)

24 (10.2)

0.046

16 (16.2)

8 (8.1)

0.082

Reoperation, n (%)

6 (4.3)

3 (1.3)

0.082

4 (4.0)

1 (1.0)

0.369

Postoperative LOS (range) (days)

9 (5–26)

9 (3–33)

0.172

9 (5–26)

8 (3–33)

0.011

30-day mortality, n (%)

0 (0)

0 (0)

1.000

0 (0)

0 (0)

1.000

Recurrence, n (%)

35 (25.4)a

34 (14.5)b

0.009

28 (28.3)a

14 (14.1)b

0.015

 Local recurrence

9 (6.5)

4 (1.7)

0.019

9 (9.1)

4 (4.0)

0.251

 Distant metastasis

28 (20.3)

32 (13.6)

0.090

21 (21.2)

12 (12.1)

0.086

  Lung

7 (5.1)

10 (4.3)

0.715

6 (6.1)

5 (5.1)

0.756

  Liver

1 (0.7)

6 (2.6)

0.267

1 (1.0)

2 (2.0)

1.000

  Other site

6 (4.3)

4 (1.7)

0.182

3 (3.0)

1 (1.0)

0.621

  Multiple organs

14 (10.1)

12 (5.1)

0.065

11 (11.1)

4 (4.0)

0.104

  1. LRC Low rectal cancer, M/HRC Mid/high rectal cancer, LAR Low anterior resection, CRM Circumferential resection margin, LOS Length of stay
  2. a/b Local recurrence and distant metastasis occurred synchronously in 2 cases both in LRC and M/HRC groups