Table 3 Characteristics of the studies included in the dose-analysis meta-analysis
From: Prognosis of pregnancy-associated breast cancer: a meta-analysis
Study ID | Time point of breast cancer diagnosis | Time after last delivery (months) | No. of participants | Adjusted HRa | 95% CI |
|---|---|---|---|---|---|
Guinee, 1994 [30] | Postpartum 1–12 m | 1–12 | 40 | 1.88 | 0.88–3.98 |
Postpartum 13–48 m | 13–48 | 51 | 1.09 | 0.54–2.19 | |
Postpartum ≥49 m | ≥49 | 35 | 0.54 | 0.19–1.55 | |
Olson, 1998 [35] | Postpartum < 24 m | 0–24 | 42 | 3.1 | 1.8–5.4 |
Postpartum ≥24 m | ≥24 | 352 | 1.3 | 0.9–2.0 | |
Reeves, 2000 [36] | Postpartum < 60 m | 0–60 | 67 | 1.56 | 1.01–2.42 |
Postpartum 60–108 m | 60–108 | 80 | 0.88 | 0.58–1.32 | |
Postpartum > 120 m | > 120 | 525 | 0.99 | 0.77–1.27 | |
Daling, 2002 [38] | Postpartum < 24 m | 0–24 | 83 | 2.3 | 1.5–3.4 |
Postpartum 24–60 m | 24–70 | 120 | 1.5 | 1.0–2.1 | |
Postpartum > 60 m | > 70 | 661 | 1.2 | 0.9–1.6 | |
Whiteman, 2004 [42] | Postpartum ≤12 m | 0–12 | 59 | 1.51 | 1.02–2.23 |
Postpartum 13–48 m | 13–48 | 213 | 1.25 | 0.95–1.64 | |
Postpartum > 48 m | > 48 | 1470 | 1.06 | 0.86–1.31 | |
Phillips, 2009 [48] | Postpartum < 24 m | 0–24 | 133 | 2.75 | 1.98–3.83 |
Postpartum 24–60 m | 24–60 | 231 | 2.2 | 1.65–2.94 | |
Postpartum ≥72 m | ≥72 | 2067 | 0.98 | 0.79–1.22 | |
Calliha, 2013 [58] | Postpartum < 60 m | 0–60 | 86 | 2.65 | 1.09–6.42 |
Postpartum ≥60 m | ≥60 | 172 | 1.52 | 0.71–3.28 | |
Nagatsuma, 2014 [63] | Postpartum ≤24 m | 0–24 | 37 | 2.19 | 1.05–4.56 |
Postpartum 36–60 m | 36–60 | 59 | 1.49 | 0.79–2.83 | |
Postpartum > 60 m | > 60 | 181 | 0.81 | 0.46–1.43 | |
Johansson, 2018 [2] | Postpartum 0–6 m | 0–6 | 41 | 1.16 | 0.64–2.14 |
Postpartum 6–12 m | 6–12 | 84 | 1.3 | 0.83–2.03 | |
Postpartum 12–24 m | 12–24 | 194 | 1.01 | 0.70–1.46 | |
Postpartum 24–60 m | 24–60 | 629 | 1.22 | 0.96–1.55 | |
Postpartum 60–120 m | 60–120 | 1106 | 1.08 | 0.87–1.53 | |
Postpartum > 120 m | > 120 | 1623 | 0.98 | 0.78–1.22 | |
Chuang, 2018 [69] | Postpartum 0–12 m | 0–12 | 347 | 1.29 | 0.96–1.74 |
Postpartum 13–24 m | 13–24 | 410 | 1.27 | 0.95–1.70 | |
Postpartum 25–60 m | 25–60 | 1583 | 1.06 | 0.88–1.27 |