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Fig. 1 | BMC Cancer

Fig. 1

From: USP18 promotes cell proliferation and suppressed apoptosis in cervical cancer cells via activating AKT signaling pathway

Fig. 1

USP18 is upregulated in human cervical cancer tissues. a USP18 is upregulated in primary cervical cancer samples. Data collected from the TCGA database CESC dataset. *** p < 0.001 vs Normal. b The relative mRNA levels of USP18 were much higher in human cervical cancer tissues than that in para-cancer tissues, n = 30 for each group. *** p < 0.001 vs Normal. c USP18 was enriched in the PI3/AKT pathway. d The relative protein levels of USP18 and AKT phosphorylation were upregulated in human cervical cancer tissues compared with that in para-cancer tissues. *** p < 0.001 vs para-carcinoma tissues. n = 4 for each group. The full-length gels are presented in Supplementary Figure 1D. e IHC staining assay indicated the positive correlation between USP18 and AKT phosphorylation in human cervical cancer tissues, n = 30 for each group

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BMC Cancer

ISSN: 1471-2407

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