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Table 1 Main characteristics of the included studies in our-analysis

From: Does hypothyroidism increase the risk of breast cancer: evidence from a meta-analysis

Study

Year

Region

Sample

Median/Mean age

Follow-up

Study design

NOS

(years)

(years)

Adami

1978

Sweden

358

64

1

Case-control

7

Kalache

1982

UK

2352

NA

11

Case-control

6

Hoffman

1984

Sweden

1665

47.2

21.9

Cohort

8

Brinton

1984

USA

2612

NA

4

Case-control

7

Moseson

1993

Canada

1101

54

4

Case-control

7

Smyth

1996

Ireland

400

57.2 ± 1.4

1

Case-control

7

Shering

1996

Ireland

350

NA

NA

Case-control

7

Talamini

1997

Italy

5157

55

3

Case-control

7

Simon

2002

USA

9257

NA

4

Case-control

6

Turken

2003

Prague

250

63

4

Case-control

6

Kuijpens

2005

Netherlands

2775

50.5

9

Cohort

8

Cristofanilli

2005

USA

2224

51.6 ± 12.6

3

Case-control

6

Sandhu

2009

Canada

179,462

74.9 ± 7

10

Cohort

8

Hellevik

2009

Norwegian

29,691

≥20

9

Cohort

7

Ditsch

2010

Germany

130

58.6 ± 13.5

NA

Case-control

7

Grani

2012

Italy

380

59

5

Case-control

7

Søgaard

2016

Danish

61,873

71

35

Cohort

7

Weng

2018

USA

103,466

53.3

NA

Case-control

8

Kim

2019

Korea

67,416

≥40

4

Cohort

8