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Fig. 5 | BMC Cancer

Fig. 5

From: Breast cancer diagnosis is associated with relative left ventricular hypertrophy and elevated endothelin-1 signaling

Fig. 5

Circulating level of big endothelin-1 correlated with pT stage of breast cancer patients with relative left ventricular hypertrophy. a Indexed left ventricular (LV) mass in pT1 stage breast cancer patients (n = 12), pT2/3 stage breast cancer patients (n = 16) and a control cohort of women with comparable baseline factors (n = 17). b Big ET-1 concentration in pT1 stage breast cancer patients (n = 12), pT2/3 stage breast cancer patients (n = 16) and a control cohort of women with comparable baseline factors (n = 17). c Correlation between big ET-1 concentration and indexed LV mass in pT1 stage breast cancer patients (n = 12), d Correlation between big ET-1 concentration and indexed LV mass in pT2/3 stage breast cancer patients (n = 16). Dots represent individual values. Results are shown as means ± SD. Comparisons between three groups were made by one-way ANOVA with a Dunnett post hoc multiple comparison test. +p < 0.05 vs healthy control. The correlations between Big ET-1 levels and indexed LV mass in pT stage of breast cancer patients was determined using Pearson’s correlation coefficient

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