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Table 3 Oncogenic potential of mutant TP53-273H in A/J and FVB/N mice

From: The oncogenic potential of a mutant TP53 gene explored in two spontaneous lung cancer mice models

 

Month ≤ 12

Month 13–15

Month 16–18

Overall

A/J-SPC-TP53-273H tumor rate

0.095

0.394

0.500

0.338

A/J-NT tumor rate

0.000

0.136

0.300

0.143

Oncogenic potential in A/J

0.095

0.258

0.200

0.184

FVB/N-SPC-TP53-273H tumor rate

0.056

0.277

0.362

0.223

FVB/N-NT tumor rate

0.039

0.057

0.100

0.057

Oncogenic potential in FVB/N

0.016

0.219

0.262

0.166