Association of MTHFR C677T polymorphism with severity and localization of chronic atrophic gastritis patients without Helicobacter pylori infection: a case control study

Table 2 Variables examined for determining the risk of moderate-to-severe lesions

Variables	Number	P Value	OR	95%CI	P Value
Age (> 55/< 55 year)	64/64	0.04	2.28	1.04–5.00	0.04
Gender (male/female)	64/64	0.85	1.07	0.40–2.82	0.90
Peptic ulcer (positive/negative)	21/107	0.66	1.33	0.56–2.76	0.59
Smoking (yes/no)	36/92	0.79	0.77	0.25–2.36	0.65
Drinking (yes/no)	33/95	0.75	1.32	0.43–4.00	0.63
BMI (kg/m²)	22.4 ± 2.7		1	0.86–1.16	0.99
Hcy (μmol/L)	12.8 ± 5.6		0.98	0.91–1.05	0.54
Family history (yes/no)	30/98	0.77	1.08	0.41–1.45	0.76
MTHFR C677T (CC + CT/TT)	100/28	0.01	4.12	1.29–13.21	0.02

Hcy Homocysteine, BMI Body mass index, OR Odds ratio, P-values were calculated using a binominal logistic regression analysis. CI Confidence interval

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