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Table 1 Helicobacter pylori-negative patients characteristics stratified by MTHFR C677T genotypes

From: Association of MTHFR C677T polymorphism with severity and localization of chronic atrophic gastritis patients without Helicobacter pylori infection: a case control study

Characteristic CC
n = 31
CT
n = 69
TT
n = 28
P Value
Age (years), mean ± SD 55 ± 10 56 ± 9 54 ± 13 N.S
 27–44 5 5 7  
 45–62 17 48 14  
 63–80 9 16 7  
Male, n (%) 15 (48.4%) 34 (49.3%) 15 (53.6%) N.S
Family history of gastric cancer in first-degree relatives, n (%) 7 (22.6%) 19 (27.5%) 4 (14.3%) N.S
Smoking status     N.S
 Never 23 50 19  
 Current/Former 8 19 9  
Alcohol status     N.S
 Never 23 53 19  
 Current/Former 8 16 9  
Gastrin-17 (pmol/L) 8.2 ± 20.6 5.8 ± 11.4 3.8 ± 6.6 N.S
Pepsinogen I (μg/L) 104.8 ± 54.8 103.6 ± 69.5 81.1 ± 31.3 N.S
Pepsinogen II (μg/L) 10.5 ± 6.3 10.1 ± 8.6 8.4 ± 3.8 N.S
PGR 11.3 ± 4.7 11.4 ± 4.0 10.5 ± 3.4 N.S
BMI (kg/m2) 22.4 ± 2.8 22.3 ± 2.8 22.6 ± 2.5 N.S
  1. CC MTHFR 677CC, CT MTHFR 677CT, TT MTHFR 677TT, SD Standard deviation, PGR Pepsinogen I and pepsinogen II ratio, Hcy Homocysteine, BMI Body mass index, N.S Not significant