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Table 5 Multivariate Cox analysis of DFS and OS in ADC

From: Comprehensive analysis of spread through air spaces in lung adenocarcinoma and squamous cell carcinoma using the 8th edition AJCC/UICC staging system

Parameters DFS OS
p HR (95% CI) p HR (95% CI)
Age > 65 vs. ≤65 0.009 2.637 (1.275–5.455)
Tumor size > 3 cm vs. ≤3 cm 0.137 1.383 (0.902–2.119)
Pleural invasion Present vs. absent 0.022 1.729 (1.084–2.757) 0.158 1.878 (0.783–4.504)
Vascular invasion Present vs. absent 0.459 1.341 (0.617–2.916)
Lymphatic invasion Present vs. absent 0.388 1.259 (0.746–2.123) 0.289 1.792 (0.610–5.266)
STAS Present vs. absent 0.002 2.460(1.398–4.327) 0.719 1.187 (0.466–3.026)
Pathological stage III, IV vs. I, II 0.241 1.321 (0.830–2.102) 0.001 3.766 (1.710–8.296)
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