BMC Cancer

Table 4 Univariate survival analysis of DFS and OS in ADC

From: Comprehensive analysis of spread through air spaces in lung adenocarcinoma and squamous cell carcinoma using the 8th edition AJCC/UICC staging system

Parameters	DFS		OS
Parameters	Mean DFS (month)	p	Mean OS (month)	p
Age
≤ 65	44.34	0.228	58.92	0.033
> 65	49.46	0.228	56.52	0.033
Tumor size
≤ 3 cm	49.61	0.002	60.22	0.054
> 3 cm	41.87	0.002	55.70	0.054
Pleural invasion
Absent	51.14	< 0.001	60.15	0.002
Present	41.18	< 0.001	55.45	0.002
Vascular invasion
Absent	49.17	0.064	60.56	0.009
Present	41.21	0.064	50.79	0.009
Lymphatic invasion
Absent	52.00	< 0.001	59.75	0.001
Present	41.40	< 0.001	55.06	0.001
Perineural invasion
Absent	47.39	0.598	59.00	0.266
Present	43.89	0.598	52.78	0.266
Pathological stage
Stage I-II	49.93	< 0.001	61.47	< 0.001
Stage III-IV	37.65	< 0.001	47.59	< 0.001
Presence of micropapillary
Absent	48.77	0.120	58.81	0.655
Present	41.98	0.120	55.58	0.655
STAS
Absent	55.73	< 0.001	60.72	0.025
Present	40.42	< 0.001	56.79	0.025
STAS (in Stage I-II)
Absent	58.20	< 0.001	62.96	0.015
Present	41.91	< 0.001	59.57	0.015
STAS (in Stage III-IV)
Absent	30.75	0.736	35.30	0.332
Present	36.88	0.736	48.87	0.332

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