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Table 4 Univariate survival analysis of DFS and OS in ADC

From: Comprehensive analysis of spread through air spaces in lung adenocarcinoma and squamous cell carcinoma using the 8th edition AJCC/UICC staging system

Parameters DFS OS
Mean DFS (month) p Mean OS (month) p
Age
  ≤ 65 44.34 0.228 58.92 0.033
  > 65 49.46 56.52
Tumor size
  ≤ 3 cm 49.61 0.002 60.22 0.054
  > 3 cm 41.87 55.70
Pleural invasion
 Absent 51.14 < 0.001 60.15 0.002
 Present 41.18 55.45
Vascular invasion
 Absent 49.17 0.064 60.56 0.009
 Present 41.21 50.79
Lymphatic invasion
 Absent 52.00 < 0.001 59.75 0.001
 Present 41.40 55.06
Perineural invasion
 Absent 47.39 0.598 59.00 0.266
 Present 43.89 52.78
Pathological stage
 Stage I-II 49.93 < 0.001 61.47 < 0.001
 Stage III-IV 37.65 47.59
Presence of micropapillary
 Absent 48.77 0.120 58.81 0.655
 Present 41.98 55.58
STAS
 Absent 55.73 < 0.001 60.72 0.025
 Present 40.42 56.79
STAS (in Stage I-II)
 Absent 58.20 < 0.001 62.96 0.015
 Present 41.91 59.57
STAS (in Stage III-IV)
 Absent 30.75 0.736 35.30 0.332
 Present 36.88 48.87