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Table 3 Correlations between immunohistochemical expression and STAS

From: Comprehensive analysis of spread through air spaces in lung adenocarcinoma and squamous cell carcinoma using the 8th edition AJCC/UICC staging system

Antibodies

In total

STAS in ADC

p

In total

STAS in SQCC

p

Positive(n(%))

Negative(n(%))

Positive(n(%))

Negative(n(%))

E-cadherin

 Low

171

119(66.9)

52(47.3)

0.001

32

16(41.0)

16(19.5)

0.012

 High

117

59(33.1)

58(52.7)

89

23(59.0)

66(80.5)

Vimentin

 Low

143

76(42.7)

67(60.9)

0.003

54

12(30.8)

42(51.2)

0.034

 High

145

102(57.3)

43(39.1)

67

27(69.2)

40(48.8)

Survivin

 Low

113

67(37.6)

46(41.8)

0.481

77

15(38.5)

62(75.6)

< 0.001

 High

175

111(62.4)

64(58.2)

44

24(61.5)

20(24.4)

Ki67

 Low

125

62(34.8)

63(57.3)

< 0.001

59

22(56.4)

37(45.1)

0.246

 High

163

116(65.2)

47(42.7)

62

17(43.6)

45(54.9)

Bcl-2

 Low

115

76(42.7)

39(35.5)

0.223

71

22(56.4)

49(59.8)

0.727

 High

173

102(57.3)

71(64.5)

50

17(43.6)

33(40.2)

Bim

 Low

135

87(48.9)

48(43.6)

0.387

61

23(59.0)

38(46.3)

0.194

 High

153

91(51.1)

62(56.4)

60

16(41.0)

44(53.7)